Detailed information NTG0940407

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: V6U63_RS09290
• Genome accession: NZ_CP145861
• Coordinates: 1998742..1999842 (-)
• Length: 366 a.a.
• NCBI ID: WP_144429890.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS3
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1993742..2004842

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U63_RS09250 (V6U63_09235)	-	1994351..1994548 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
V6U63_RS09255 (V6U63_09240)	-	1994799..1995992 (-)	1194	WP_410535066.1	acetate kinase	-
V6U63_RS09260 (V6U63_09245)	comYH	1996049..1997005 (-)	957	WP_227071975.1	class I SAM-dependent methyltransferase	Machinery gene
V6U63_RS09265 (V6U63_09250)	comGG	1997050..1997367 (-)	318	WP_227071976.1	competence type IV pilus minor pilin ComGG	-
V6U63_RS09270 (V6U63_09255)	comYF	1997345..1997782 (-)	438	WP_227071977.1	competence type IV pilus minor pilin ComGF	Machinery gene
V6U63_RS09275 (V6U63_09260)	comGE	1997769..1997999 (-)	231	WP_021144685.1	competence type IV pilus minor pilin ComGE	-
V6U63_RS09280 (V6U63_09265)	comYD	1998031..1998459 (-)	429	WP_253183813.1	competence type IV pilus minor pilin ComGD	Machinery gene
V6U63_RS09285 (V6U63_09270)	comYC	1998419..1998745 (-)	327	WP_002885815.1	competence type IV pilus major pilin ComGC	Machinery gene
V6U63_RS09290 (V6U63_09275)	comYB	1998742..1999842 (-)	1101	WP_144429890.1	competence type IV pilus assembly protein ComGB	Machinery gene
V6U63_RS09295 (V6U63_09280)	comYA	1999724..2000665 (-)	942	WP_002885658.1	competence type IV pilus ATPase ComGA	Machinery gene
V6U63_RS09300 (V6U63_09285)	-	2000747..2001109 (-)	363	WP_002887019.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41648.61 Da
• Isoelectric Point: 9.9778

>NTDB_id=940407 V6U63_RS09290 WP_144429890.1 1998742..1999842(-) (comYB) [Streptococcus salivarius strain KSS3]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSNLFRELGADLEEALMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=940407 V6U63_RS09290 WP_144429890.1 1998742..1999842(-) (comYB) [Streptococcus salivarius strain KSS3]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGCATGACCAAGGTTC
GCAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCCCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ACCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCTAATCTCTTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTACTCACCCTTTTTTCACTAAGG
AACTATCCTTGATTATTGCTTATGGAGAGGCCAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCTATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	55.102	93.716	0.516
comYB	Streptococcus mutans UA159	55.102	93.716	0.516
comYB	Streptococcus gordonii str. Challis substr. CH1	51.02	93.716	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.144	94.809	0.475
comGB/cglB	Streptococcus mitis SK321	49.704	92.35	0.459
comGB/cglB	Streptococcus pneumoniae Rx1	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae D39	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae R6	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae TIGR4	49.408	92.35	0.456
comGB	Lactococcus lactis subsp. cremoris KW2	45.646	90.984	0.415