Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   V6U63_RS01450 Genome accession   NZ_CP145861
Coordinates   269810..271906 (+) Length   698 a.a.
NCBI ID   WP_272159129.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS3     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 264810..276906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U63_RS01425 (V6U63_01430) trkA 264901..266250 (-) 1350 WP_014633874.1 Trk system potassium transporter TrkA -
  V6U63_RS01430 (V6U63_01435) - 266528..267037 (+) 510 WP_118172046.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  V6U63_RS01435 (V6U63_01440) - 267348..267905 (+) 558 WP_037598980.1 ECF transporter S component -
  V6U63_RS01440 (V6U63_01445) - 267908..268558 (+) 651 WP_048673883.1 phosphatase PAP2 family protein -
  V6U63_RS01445 (V6U63_01450) comR 268736..269635 (+) 900 WP_247922399.1 XRE family transcriptional regulator Regulator
  V6U63_RS01450 (V6U63_01455) comA 269810..271906 (+) 2097 WP_272159129.1 peptide cleavage/export ABC transporter Regulator
  V6U63_RS01455 (V6U63_01460) - 272018..272350 (+) 333 WP_014633880.1 DUF805 domain-containing protein -
  V6U63_RS01460 (V6U63_01465) - 272402..273793 (-) 1392 WP_410535181.1 DUF4153 domain-containing protein -
  V6U63_RS01465 (V6U63_01470) - 274183..275031 (+) 849 WP_201710915.1 amino acid ABC transporter substrate-binding protein -
  V6U63_RS01470 (V6U63_01475) - 275191..276093 (+) 903 WP_002886572.1 MetQ/NlpA family ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78527.53 Da        Isoelectric Point: 9.1072

>NTDB_id=940359 V6U63_RS01450 WP_272159129.1 269810..271906(+) (comA) [Streptococcus salivarius strain KSS3]
MSKYPYISQVDQRDCGVAALSMILKHYGSTYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQESLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAL
KCVSHRFSYQQETLSKVDLTIHKGEKIALMGKSGSGKTTLAKILSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLTKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=940359 V6U63_RS01450 WP_272159129.1 269810..271906(+) (comA) [Streptococcus salivarius strain KSS3]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGTCCATGATTCTTAAACACTA
TGGTTCGACTTATAGTTTGGCCTATTTGCGGGAGTTGGCTCAGACCTCTCGGGAAGGAACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAGCCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGACTGCAACATTATTATACAGTGTTTGGTCAAATCAAAGGGAAGCTTGT
TATTGGCGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGCTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTAACCATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGGAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCCTACCGATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACATCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCAATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCCCTTATTTTACAAAATCAGTCACTTTTTGTGATGACACTCACGGTAGTTCCTCTTTATGTGTTAATCATT
TTGGCATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAGAGACGGTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAATCTTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGACAGCTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCCAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCCTTTAAACAACTTGCTCTT
AAGTGTGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGGTTGATTTAACGATTCATAAGGGGGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACGACCTTGGCTAAAATATTGTCGGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGACGCTATTAGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTCACAGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGATGAGAAAAAGCTTCTTAAGGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAGGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCGAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTACTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCGGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter transmembrane region (ABC_membrane)

(167-436)

ABC transporter (ABC_tran)

(494-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.546

98.997

0.53
  comA Streptococcus gordonii str. Challis substr. CH1

52.73

99.713

0.526
  comA Streptococcus mitis NCTC 12261

53.111

98.997

0.526
  comA Streptococcus pneumoniae Rx1

52.967

98.997

0.524
  comA Streptococcus pneumoniae D39

52.967

98.997

0.524
  comA Streptococcus pneumoniae R6

52.967

98.997

0.524
  comA Streptococcus pneumoniae TIGR4

52.822

98.997

0.523
  comA/nlmT Streptococcus mutans UA159

50

98.854

0.494