Detailed information NTG0940281

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: V6U62_RS00020
• Genome accession: NZ_CP145860
• Coordinates: 3631..4866 (-)
• Length: 411 a.a.
• NCBI ID: WP_048676433.1
• Uniprot ID: A0AB35IU66
• Organism: Streptococcus salivarius strain KSS2
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1..9866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U62_RS00010 (V6U62_00010)	dnaA	1196..2560 (-)	1365	WP_048676427.1	chromosomal replication initiator protein DnaA	-
V6U62_RS00015 (V6U62_00015)	spo0J	2798..3565 (-)	768	WP_195187629.1	ParB/RepB/Spo0J family partition protein	Regulator
V6U62_RS00020 (V6U62_00020)	htrA	3631..4866 (-)	1236	WP_048676433.1	S1C family serine protease	Regulator
V6U62_RS00025 (V6U62_00025)	rlmH	5072..5551 (+)	480	WP_014632473.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
V6U62_RS00030 (V6U62_00030)	-	5567..6250 (+)	684	WP_013991345.1	YoaK family protein	-
V6U62_RS00050 (V6U62_00050)	-	6801..9395 (-)	2595	WP_195914756.1	YfhO family protein	-

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42942.12 Da
• Isoelectric Point: 4.6266

>NTDB_id=940281 V6U62_RS00020 WP_048676433.1 3631..4866(-) (htrA) [Streptococcus salivarius strain KSS2]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSNQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=940281 V6U62_RS00020 WP_048676433.1 3631..4866(-) (htrA) [Streptococcus salivarius strain KSS2]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTACTAGGTGGTTTACTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGATCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAACCAAGACAAATCAAA
AGATTCTGATGGGTTGCAAGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGGAAAGAGGCCTACATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGTGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAACAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (7-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.538	98.054	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	57.635	98.783	0.569
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus mitis NCTC 12261	54.279	99.513	0.54