Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   V6T26_RS05470 Genome accession   NZ_CP145858
Coordinates   1200903..1201610 (-) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain KSS11     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1195903..1206610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS05445 (V6T26_05445) yidA 1196257..1197066 (+) 810 WP_145516925.1 sugar-phosphatase -
  V6T26_RS05450 (V6T26_05450) - 1197068..1198282 (+) 1215 WP_371595679.1 aminoacyltransferase -
  V6T26_RS05455 (V6T26_05455) - 1198334..1198693 (-) 360 WP_371595678.1 YbaN family protein -
  V6T26_RS05460 (V6T26_05460) vicX 1198752..1199564 (-) 813 WP_371595677.1 MBL fold metallo-hydrolase Regulator
  V6T26_RS05465 (V6T26_05465) vicK 1199570..1200910 (-) 1341 WP_410541045.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6T26_RS05470 (V6T26_05470) vicR 1200903..1201610 (-) 708 WP_002884978.1 response regulator YycF Regulator
  V6T26_RS05475 (V6T26_05475) - 1201896..1202663 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  V6T26_RS05480 (V6T26_05480) - 1202673..1203506 (+) 834 WP_410541046.1 transporter substrate-binding domain-containing protein -
  V6T26_RS05485 (V6T26_05485) - 1203524..1204222 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  V6T26_RS05490 (V6T26_05490) - 1204234..1204884 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6T26_RS05495 (V6T26_05495) - 1205073..1205840 (+) 768 WP_151405000.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=940251 V6T26_RS05470 WP_002884978.1 1200903..1201610(-) (vicR) [Streptococcus salivarius strain KSS11]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=940251 V6T26_RS05470 WP_002884978.1 1200903..1201610(-) (vicR) [Streptococcus salivarius strain KSS11]
ATGAAAAAAATTCTAGTAGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAATCTGACTAAAGAGGGTTATGA
AGTTGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCAATTATCATGCTTTCCGCT
AAGGATAGTGAGTTCGATAAGGTTATCGGGCTAGAAATTGGGGCAGATGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCAGGCA
AGCAGGAAATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAACTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTAATGACGCGTGAACATTTGCTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGACA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387