Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ENLAB_RS03815 Genome accession   NZ_AP025635
Coordinates   823374..824678 (+) Length   434 a.a.
NCBI ID   WP_008379110.1    Uniprot ID   A0A242CMI6
Organism   Enterococcus innesii strain DB-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 818374..829678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ENLAB_RS03795 (ENLAB_07630) msrA 819840..820763 (-) 924 WP_244352709.1 peptide-methionine (S)-S-oxide reductase MsrA -
  ENLAB_RS03800 (ENLAB_07640) map 820905..821675 (-) 771 WP_244352711.1 type I methionyl aminopeptidase -
  ENLAB_RS03805 (ENLAB_07650) truA 821718..822455 (-) 738 WP_086291979.1 tRNA pseudouridine(38-40) synthase TruA -
  ENLAB_RS03810 (ENLAB_07660) rlmH 822521..823000 (-) 480 WP_244352713.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ENLAB_RS03815 (ENLAB_07670) htrA 823374..824678 (+) 1305 WP_008379110.1 S1C family serine protease Regulator
  ENLAB_RS03820 (ENLAB_07680) ytpR 824747..825361 (-) 615 WP_244352714.1 YtpR family tRNA-binding protein -
  ENLAB_RS03825 (ENLAB_07690) - 825635..826096 (-) 462 WP_140965803.1 universal stress protein -
  ENLAB_RS03830 (ENLAB_07700) - 826109..826429 (-) 321 WP_026008043.1 thioredoxin family protein -
  ENLAB_RS03835 (ENLAB_07710) pepA 826562..827638 (-) 1077 WP_034878843.1 glutamyl aminopeptidase -
  ENLAB_RS03840 (ENLAB_07720) - 827931..828275 (+) 345 WP_005225425.1 peptidase -
  ENLAB_RS03845 (ENLAB_07730) - 828336..829370 (-) 1035 WP_244352715.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44857.36 Da        Isoelectric Point: 4.0123

>NTDB_id=93337 ENLAB_RS03815 WP_008379110.1 823374..824678(+) (htrA) [Enterococcus innesii strain DB-1]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSEDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDSYTDLAVLKISSEKVTTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=93337 ENLAB_RS03815 WP_008379110.1 823374..824678(+) (htrA) [Enterococcus innesii strain DB-1]
ATGGCAAGAAAATATGTCACACCAGGTAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGGTCATCTTTGACTTCAACCCCAGAAACCACGA
CTAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAA
GCAGTTGAAAAAGTACAAGATTCCGTCGTTTCCATCATTAATTTACAACAAAGTCAAAGCAACGATTGGAACAGCCTCTT
TGGTCAGCAAGGTGGACAAAGTGAAGGCGATAGCCAAAGCGAAGACGACAGCGCCTTAGAAGCTTCTTCTGAAGGAAGTG
GTGTCATCTACAAAATTGATGGCGACGATGCCTATGTCGTAACCAACAACCACGTAGTTGAAGGTCAAGATGGTTTGGAA
GTTGTCTTAGCAGATGGTACGAAAGTCAAAGCTGAATTGGTAGGTACCGATTCTTACACAGACTTAGCCGTATTAAAAAT
CTCTTCTGAAAAAGTTACAACTGCCGCAACATTTGGCGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCAATCGCGATCG
GTTCTCCTCTAGGCTCTGACTATGCAAACTCTGTGACACAAGGGATCGTGTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAGTCTGGTGGTACGATCAGTATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGGAACTCAGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCGGGCTCTGCTTCAGGCGTTAGTG
TCGAAGGAATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTC
CGCCCTGCACTAGGTATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCTGTAACTTCAGGCGTTGTGATCTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATCACGAAGATCGATGATACAGAAGTCAGCACCACAACTGATCTGCAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACAGCAGAAGTAAAACTTTCCGTTGATACATCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(18-420)

PDZ domain (PDZ_2)

(322-419)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A242CMI6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.927

91.475

0.521
  htrA Streptococcus gordonii str. Challis substr. CH1

51.074

96.544

0.493
  htrA Streptococcus mitis NCTC 12261

55.989

82.719

0.463
  htrA Streptococcus pneumoniae TIGR4

57.602

78.802

0.454
  htrA Streptococcus pneumoniae D39

57.602

78.802

0.454
  htrA Streptococcus pneumoniae Rx1

57.602

78.802

0.454
  htrA Streptococcus pneumoniae R6

57.602

78.802

0.454

Multiple sequence alignment