Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   V3435_RS00425 Genome accession   NZ_CP144270
Coordinates   74210..74779 (+) Length   189 a.a.
NCBI ID   WP_000872866.1    Uniprot ID   -
Organism   Staphylococcus aureus strain LA52     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 69210..79779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3435_RS00400 (V3435_00400) cysE 70422..71069 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  V3435_RS00405 (V3435_00405) cysS 71053..72453 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  V3435_RS00410 (V3435_00410) - 72446..72850 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  V3435_RS00415 (V3435_00415) rlmB 72858..73604 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  V3435_RS00420 (V3435_00420) - 73604..74128 (+) 525 WP_000664738.1 NYN domain-containing protein -
  V3435_RS00425 (V3435_00425) sigH 74210..74779 (+) 570 WP_000872866.1 RNA polymerase sigma factor Regulator
  V3435_RS00430 (V3435_00430) rpmG 74894..75037 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  V3435_RS00435 (V3435_00435) secE 75093..75275 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  V3435_RS00440 (V3435_00440) nusG 75288..75836 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  V3435_RS00445 (V3435_00445) rplK 76017..76439 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  V3435_RS00450 (V3435_00450) rplA 76647..77339 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  V3435_RS00455 (V3435_00455) rplJ 77611..78111 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  V3435_RS00460 (V3435_00460) rplL 78154..78522 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  V3435_RS00465 (V3435_00465) - 78697..79305 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=933092 V3435_RS00425 WP_000872866.1 74210..74779(+) (sigH) [Staphylococcus aureus strain LA52]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRCIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=933092 V3435_RS00425 WP_000872866.1 74210..74779(+) (sigH) [Staphylococcus aureus strain LA52]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGATGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974