Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   AB5J49_RS11725 Genome accession   NZ_CP163439
Coordinates   2672286..2675333 (-) Length   1015 a.a.
NCBI ID   WP_369168518.1    Uniprot ID   -
Organism   Streptomyces sp. R28     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2667286..2680333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB5J49_RS11705 (AB5J49_11705) - 2667867..2668040 (+) 174 WP_369168513.1 hypothetical protein -
  AB5J49_RS11710 (AB5J49_11710) - 2668749..2669699 (+) 951 WP_369168514.1 hypothetical protein -
  AB5J49_RS11715 (AB5J49_11715) - 2670058..2671224 (+) 1167 WP_369168515.1 LacI family DNA-binding transcriptional regulator -
  AB5J49_RS11720 (AB5J49_11720) - 2671221..2672192 (+) 972 WP_369168517.1 carbohydrate kinase -
  AB5J49_RS11725 (AB5J49_11725) uvrA 2672286..2675333 (-) 3048 WP_369168518.1 excinuclease ABC subunit UvrA Machinery gene
  AB5J49_RS11730 (AB5J49_11730) - 2675557..2676243 (+) 687 WP_369168519.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  AB5J49_RS11735 (AB5J49_11735) - 2676289..2676945 (+) 657 WP_369168520.1 MBL fold metallo-hydrolase -
  AB5J49_RS11740 (AB5J49_11740) - 2677290..2678174 (+) 885 WP_369168521.1 ABC transporter substrate-binding protein -
  AB5J49_RS11745 (AB5J49_11745) - 2678171..2679091 (+) 921 WP_369168522.1 amino acid ABC transporter permease -
  AB5J49_RS11750 (AB5J49_11750) - 2679112..2679840 (+) 729 WP_369175105.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 1015 a.a.        Molecular weight: 111397.64 Da        Isoelectric Point: 8.2260

>NTDB_id=925244 AB5J49_RS11725 WP_369168518.1 2672286..2675333(-) (uvrA) [Streptomyces sp. R28]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPQCSRPISRQSPQAIVDRVLELPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGETIQLSNPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPECTGIGTRMEVDPELIVPDEDKSLDEGAIHPWSHGHTK
DYFGRLIGALADALGFRTDIPFAGLPQRAKKALLHGHKTQIEVRYRNRYGRERVYTTPFEGAVPFVKRRHSEAESDASRE
RFEGYMREVPCPTCEGTRLKPIVLAVTIMERSIAEVAAMSISDCADFLGKLKLNARDKKIAERVLKEVNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKTAD
WVVDIGPGAGEHGGKVVHSGSLKELLANPESQTGQYLSGKRSIPLPDIRRPQDPSRRLTVHGARENNLQDIDVSFPLGLF
TAVTGVSGSGKSTLVNDILYTHLARELNGARNVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHIRKLFA
ETTEAKVRGYMPGRFSFNVKGGRCENCAGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSISEVLNMPIEEA
MDFFEAVPAINRHLKTLNDVGLGYVRLGQSATTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLLKVLA
GLVDKGNTVIVIEHNLDVIKTADWVVDMGPEGGAGGGLVIAEGTPEEVAGVPTSHTGKFLREILGADRISDAASVKAPRK
AAAKKTVAAGSTAKKTATARTAKTTKAANNTATKKAAGATKKAAPAKKTTRARKA

Nucleotide


Download         Length: 3048 bp        

>NTDB_id=925244 AB5J49_RS11725 WP_369168518.1 2672286..2675333(-) (uvrA) [Streptomyces sp. R28]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAACCTGAAGAATGTCTCGCTCGACCTGCCGCGCGACTCGCT
CATCGTCTTCACGGGCCTGTCGGGGTCGGGTAAGTCCTCGCTGGCCTTCGACACCATCTTCGCCGAGGGGCAGCGGCGCT
ACGTGGAGTCGCTGTCGTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAAGGTCTG
TCCCCGGCGGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTGCGTCTGCTCTTCGCGCGTATCGGCAAGCCGCACTGCCCCCAGTGCAGCCGCCCGATCTCGCGCCAGTCGCCGC
AGGCCATCGTCGACAGGGTTCTGGAGCTGCCGGAGGGGAGCCGCTTCCAGGTGCTGTCGCCGCTGGTGCGTGAGCGCAAG
GGCGAGTTCGTCGACCTGTTCGCCGATCTTCAGACCAAGGGCTACTCCCGCGCGCGGGTGGACGGCGAGACGATCCAGCT
CTCCAACCCGCCGACGCTGAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGTCTCACGGTGAAGGACTCCG
CCAAGCGCCGCCTCACCGACTCCGTGGAGACCGCCCTCGGCCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGCATGTACTCGGAGCACCTGTACTGCCCGTACGACGACCTCTCCTTCGAGGAGCT
GGAGCCGCGCTCCTTCTCCTTCAACTCGCCCTTCGGTGCCTGCCCCGAGTGCACCGGTATCGGGACGCGCATGGAGGTCG
ACCCCGAGCTGATCGTCCCGGACGAGGACAAGTCCCTCGACGAGGGCGCCATCCACCCCTGGTCGCACGGGCACACCAAG
GACTACTTCGGTCGCCTGATCGGTGCCCTCGCCGACGCGCTCGGCTTCCGGACGGACATCCCCTTCGCGGGCCTGCCGCA
GCGCGCCAAGAAGGCCCTCCTCCACGGGCACAAGACGCAGATCGAGGTCCGCTACCGGAACAGGTACGGCCGCGAGCGCG
TGTACACCACGCCCTTCGAGGGTGCCGTCCCCTTCGTGAAGCGCCGGCACAGCGAGGCCGAGAGCGACGCCAGCCGTGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGTGAGGGCACGCGCCTGAAGCCGATCGTCCTCGCGGTCAC
GATCATGGAGAGGTCGATCGCCGAAGTCGCCGCGATGTCCATCAGCGACTGCGCGGACTTCCTGGGCAAGCTGAAGCTCA
ACGCCCGCGACAAGAAGATCGCCGAACGCGTGCTGAAGGAGGTCAACGAGCGGCTGCGCTTCCTGGTCGACGTCGGCCTG
GACTACCTCTCGCTCAACCGCGCGGCGGGCACGCTCTCCGGCGGCGAGGCCCAGCGCATCCGCCTGGCCACCCAGATCGG
TTCCGGACTCGTCGGCGTCCTGTACGTCCTCGACGAGCCCTCCATCGGTCTGCACCAGCGCGACAACCACCGGCTCATCG
AGACCCTCGTCCGGCTGCGCGACATGGGCAACACACTCATCGTCGTCGAGCACGACGAGGACACCATCAAGACCGCCGAC
TGGGTCGTCGACATCGGCCCCGGCGCCGGTGAGCACGGCGGCAAGGTCGTGCACAGCGGCTCCCTGAAGGAGCTGCTCGC
CAACCCCGAGTCGCAGACCGGGCAGTACCTGTCCGGCAAGAGGTCCATCCCGCTGCCCGACATCCGGCGCCCGCAGGACC
CGTCCCGCCGGCTCACGGTGCACGGCGCCCGCGAGAACAACCTCCAGGACATCGACGTGTCCTTCCCGCTGGGCCTGTTC
ACCGCGGTCACCGGCGTCTCCGGCTCCGGCAAGTCGACGCTGGTCAACGACATCCTGTACACGCACCTGGCCCGAGAGCT
CAACGGCGCGCGCAACGTCCCCGGGCGGCACACGCGCGTGGACGGTGACGACCTCGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCCATCGGCCGCACCCCGCGCTCGAACCCGGCGACGTACACCGGCGTCTTCGACCACATTCGCAAGCTGTTCGCC
GAGACCACCGAGGCGAAGGTCCGTGGCTACATGCCGGGCCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAACTG
CGCGGGCGACGGCACGATCAAGATCGAGATGAACTTCCTCCCGGACGTCTACGTCCCGTGCGAGGTCTGCCACGGCGCCC
GGTACAACCGGGAGACCCTGGAGGTCCACTACAAGGGCAAGTCCATCTCCGAGGTCCTGAACATGCCGATCGAGGAAGCC
ATGGACTTCTTCGAGGCCGTCCCGGCGATCAACCGCCACCTCAAGACGCTGAACGACGTCGGTCTCGGCTATGTGCGGCT
CGGCCAGTCCGCGACCACCCTGTCCGGCGGTGAGGCGCAGCGGGTGAAGCTCGCCAGCGAACTGCAGAAGCGCTCCACCG
GCCGTACGGTCTACGTCCTCGACGAGCCGACCACCGGTCTGCACTTCGAGGACATCAGCAAGCTGCTGAAGGTCCTGGCA
GGCCTGGTCGACAAGGGCAACACGGTCATCGTCATCGAGCACAACCTCGACGTGATCAAGACAGCCGACTGGGTCGTGGA
CATGGGTCCCGAGGGCGGCGCCGGCGGTGGCCTCGTCATCGCCGAGGGCACACCCGAGGAGGTCGCCGGAGTGCCCACCA
GCCACACCGGCAAGTTCCTGCGCGAGATCCTCGGCGCCGACCGGATCAGCGACGCGGCCTCGGTGAAGGCCCCGCGCAAG
GCGGCAGCCAAGAAGACCGTCGCGGCGGGATCGACGGCGAAGAAGACGGCGACGGCCAGGACCGCGAAGACGACCAAGGC
CGCCAACAACACCGCCACGAAGAAGGCGGCCGGCGCCACGAAGAAGGCGGCACCCGCGAAGAAGACGACGCGGGCCCGCA
AGGCCTGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(628-864)

UvrA interaction domain (UvrA_inter)

(131-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.354

93.103

0.534
  uvrA Streptococcus pneumoniae TIGR4

57.354

93.103

0.534
  uvrA Streptococcus pneumoniae D39

57.354

93.103

0.534