Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   VKP40_RS00335 Genome accession   NZ_CP142355
Coordinates   54358..54456 (+) Length   32 a.a.
NCBI ID   WP_020833188.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain A946     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 49358..59456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP40_RS00320 (VKP40_00320) - 50223..51563 (+) 1341 WP_326675814.1 hypothetical protein -
  VKP40_RS00325 (VKP40_00325) purB 51932..53224 (+) 1293 WP_111686141.1 adenylosuccinate lyase -
  VKP40_RS00330 (VKP40_00330) comR 53356..54267 (+) 912 WP_326675816.1 helix-turn-helix domain-containing protein Regulator
  VKP40_RS00335 (VKP40_00335) comS 54358..54456 (+) 99 WP_020833188.1 quorum-sensing system DWW-type pheromone Regulator
  VKP40_RS00340 (VKP40_00340) ruvB 54487..55485 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  VKP40_RS00345 (VKP40_00345) - 55623..56060 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  VKP40_RS00350 (VKP40_00350) - 56083..56484 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  VKP40_RS00355 (VKP40_00355) - 56481..58256 (+) 1776 WP_136108488.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 32 a.a.        Molecular weight: 3758.63 Da        Isoelectric Point: 10.7919

>NTDB_id=925245 VKP40_RS00335 WP_020833188.1 54358..54456(+) (comS) [Streptococcus pyogenes strain A946]
MLKKVKPFLLLAAVVAFKVARVMHEFDWWNLG

Nucleotide


Download         Length: 99 bp        

>NTDB_id=925245 VKP40_RS00335 WP_020833188.1 54358..54456(+) (comS) [Streptococcus pyogenes strain A946]
ATGTTAAAAAAAGTTAAGCCATTTTTACTATTAGCCGCAGTAGTTGCATTTAAAGTTGCTCGTGTAATGCATGAATTTGA
TTGGTGGAATCTTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

100

100

1
  comS Streptococcus pyogenes MGAS8232

45.161

96.875

0.437