Detailed information NTG0925221

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: VKP53_RS04695
• Genome accession: NZ_CP142354
• Coordinates: 928914..929750 (-)
• Length: 278 a.a.
• NCBI ID: WP_014407585.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 6745-99
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 923914..934750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP53_RS04675 (VKP53_04675)	-	924269..925124 (-)	856	Protein_865	D-lactate dehydrogenase	-
VKP53_RS04680 (VKP53_04680)	-	925139..925705 (-)	567	Protein_866	PTS sugar transporter subunit IIC	-
VKP53_RS04685 (VKP53_04685)	-	925745..926602 (+)	858	Protein_867	LysR family transcriptional regulator	-
VKP53_RS04690 (VKP53_04690)	topA	926677..928806 (-)	2130	WP_014407586.1	type I DNA topoisomerase	-
VKP53_RS04695 (VKP53_04695)	dprA	928914..929750 (-)	837	WP_014407585.1	DNA-processing protein DprA	Machinery gene
VKP53_RS04700 (VKP53_04700)	-	929815..930606 (-)	792	WP_002995007.1	ribonuclease HII	-
VKP53_RS04705 (VKP53_04705)	ylqF	930596..931444 (-)	849	WP_014407584.1	ribosome biogenesis GTPase YlqF	-
VKP53_RS04710 (VKP53_04710)	-	931663..932103 (+)	441	WP_085634295.1	DUF1836 domain-containing protein	-
VKP53_RS04715 (VKP53_04715)	trhA	932100..932750 (+)	651	WP_136047671.1	PAQR family membrane homeostasis protein TrhA	-
VKP53_RS04720 (VKP53_04720)	-	932867..933778 (+)	912	WP_136047672.1	diacylglycerol/lipid kinase family protein	-
VKP53_RS04725 (VKP53_04725)	-	933828..934199 (-)	372	WP_032463865.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=925221 VKP53_RS04695 WP_014407585.1 928914..929750(-) (dprA) [Streptococcus pyogenes strain 6745-99]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=925221 VKP53_RS04695 WP_014407585.1 928914..929750(-) (dprA) [Streptococcus pyogenes strain 6745-99]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367