Detailed information NTG0925051

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: VKP55_RS04420
• Genome accession: NZ_CP142351
• Coordinates: 874497..875333 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain SS1366
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 869497..880333

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP55_RS04390 (VKP55_04390)	-	869979..870419 (+)	441	WP_009880949.1	hypothetical protein	-
VKP55_RS04395 (VKP55_04395)	-	870469..871380 (-)	912	WP_326674525.1	diacylglycerol kinase family protein	-
VKP55_RS04400 (VKP55_04400)	trhA	871497..872147 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
VKP55_RS04405 (VKP55_04405)	-	872144..872584 (-)	441	WP_326674527.1	DUF1836 domain-containing protein	-
VKP55_RS04410 (VKP55_04410)	ylqF	872803..873651 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
VKP55_RS04415 (VKP55_04415)	-	873641..874432 (+)	792	WP_023080250.1	ribonuclease HII	-
VKP55_RS04420 (VKP55_04420)	dprA	874497..875333 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
VKP55_RS04425 (VKP55_04425)	topA	875440..877569 (+)	2130	WP_002984618.1	type I DNA topoisomerase	-
VKP55_RS04430 (VKP55_04430)	trmFO	877704..879050 (+)	1347	WP_021733693.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=925051 VKP55_RS04420 WP_002995009.1 874497..875333(+) (dprA) [Streptococcus pyogenes strain SS1366]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=925051 VKP55_RS04420 WP_002995009.1 874497..875333(+) (dprA) [Streptococcus pyogenes strain SS1366]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367