Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VKP56_RS08995 Genome accession   NZ_CP142350
Coordinates   1803018..1804241 (+) Length   407 a.a.
NCBI ID   WP_326657085.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SS1445     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1798018..1809241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP56_RS08980 (VKP56_08980) - 1801158..1801932 (-) 775 Protein_1712 IS30 family transposase -
  VKP56_RS08990 (VKP56_08990) rlmH 1802327..1802806 (-) 480 WP_002981964.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VKP56_RS08995 (VKP56_08995) htrA 1803018..1804241 (+) 1224 WP_326657085.1 S1C family serine protease Regulator
  VKP56_RS09000 (VKP56_09000) spo0J 1804330..1805106 (+) 777 WP_326657087.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42827.46 Da        Isoelectric Point: 7.3103

>NTDB_id=925019 VKP56_RS08995 WP_326657085.1 1803018..1804241(+) (htrA) [Streptococcus pyogenes strain SS1445]
MPSMKYILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGNNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVIAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=925019 VKP56_RS08995 WP_326657085.1 1803018..1804241(+) (htrA) [Streptococcus pyogenes strain SS1445]
ATGCCAAGTATGAAATATATCTTAAAATCCTTAAGTATTTTACTAATTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTCAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGAATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGACTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAACAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGACGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAATAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(301-396)

Trypsin-like peptidase domain (Trypsin_2)

(109-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.881

99.263

0.614
  htrA Streptococcus gordonii str. Challis substr. CH1

55.473

98.771

0.548
  htrA Streptococcus mitis NCTC 12261

53.071

100

0.531
  htrA Streptococcus pneumoniae Rx1

53.383

98.034

0.523
  htrA Streptococcus pneumoniae D39

53.383

98.034

0.523
  htrA Streptococcus pneumoniae R6

53.383

98.034

0.523
  htrA Streptococcus pneumoniae TIGR4

53.383

98.034

0.523