Detailed information NTG0924998

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: VKP56_RS04315
• Genome accession: NZ_CP142350
• Coordinates: 864140..864976 (+)
• Length: 278 a.a.
• NCBI ID: WP_111693218.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain SS1445
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 859140..869976

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP56_RS04285 (VKP56_04285)	-	859694..860062 (+)	369	WP_010922310.1	hypothetical protein	-
VKP56_RS04290 (VKP56_04290)	-	860112..861023 (-)	912	WP_115354121.1	diacylglycerol/lipid kinase family protein	-
VKP56_RS04295 (VKP56_04295)	trhA	861140..861790 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
VKP56_RS04300 (VKP56_04300)	-	861787..862227 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
VKP56_RS04305 (VKP56_04305)	ylqF	862446..863294 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
VKP56_RS04310 (VKP56_04310)	-	863284..864075 (+)	792	WP_011285534.1	ribonuclease HII	-
VKP56_RS04315 (VKP56_04315)	dprA	864140..864976 (+)	837	WP_111693218.1	DNA-processing protein DprA	Machinery gene
VKP56_RS04320 (VKP56_04320)	topA	865083..867212 (+)	2130	WP_115354118.1	type I DNA topoisomerase	-
VKP56_RS04325 (VKP56_04325)	-	867288..868145 (-)	858	Protein_809	LysR family transcriptional regulator	-
VKP56_RS04330 (VKP56_04330)	-	868185..868751 (+)	567	Protein_810	PTS sugar transporter subunit IIC	-
VKP56_RS04335 (VKP56_04335)	-	868766..869758 (+)	993	Protein_811	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31073.07 Da
• Isoelectric Point: 9.2565

>NTDB_id=924998 VKP56_RS04315 WP_111693218.1 864140..864976(+) (dprA) [Streptococcus pyogenes strain SS1445]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=924998 VKP56_RS04315 WP_111693218.1 864140..864976(+) (dprA) [Streptococcus pyogenes strain SS1445]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367