Detailed information NTG0924944

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: VKP35_RS05110
• Genome accession: NZ_CP142349
• Coordinates: 999770..1000606 (+)
• Length: 278 a.a.
• NCBI ID: WP_111693218.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 11RS100
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 994770..1005606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP35_RS05080 (VKP35_05080)	-	995252..995692 (+)	441	WP_009880949.1	hypothetical protein	-
VKP35_RS05085 (VKP35_05085)	-	995742..996653 (-)	912	WP_002984631.1	diacylglycerol/lipid kinase family protein	-
VKP35_RS05090 (VKP35_05090)	trhA	996770..997420 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
VKP35_RS05095 (VKP35_05095)	-	997417..997857 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
VKP35_RS05100 (VKP35_05100)	ylqF	998076..998924 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
VKP35_RS05105 (VKP35_05105)	-	998914..999705 (+)	792	WP_111713259.1	ribonuclease HII	-
VKP35_RS05110 (VKP35_05110)	dprA	999770..1000606 (+)	837	WP_111693218.1	DNA-processing protein DprA	Machinery gene
VKP35_RS05115 (VKP35_05115)	topA	1000713..1002842 (+)	2130	WP_111713260.1	type I DNA topoisomerase	-
VKP35_RS05120 (VKP35_05120)	trmFO	1002977..1004323 (+)	1347	WP_111713261.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31073.07 Da
• Isoelectric Point: 9.2565

>NTDB_id=924944 VKP35_RS05110 WP_111693218.1 999770..1000606(+) (dprA) [Streptococcus pyogenes strain 11RS100]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=924944 VKP35_RS05110 WP_111693218.1 999770..1000606(+) (dprA) [Streptococcus pyogenes strain 11RS100]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367