Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   VOI49_RS10570 Genome accession   NZ_CP142018
Coordinates   2103147..2104367 (+) Length   406 a.a.
NCBI ID   WP_003048956.1    Uniprot ID   A0A380JYG2
Organism   Streptococcus dysgalactiae strain lu24     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2098147..2109367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS10545 - 2099093..2101699 (+) 2607 WP_003053215.1 YfhO family protein -
  VOI49_RS10565 rlmH 2102458..2102937 (-) 480 WP_226314022.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  VOI49_RS10570 htrA 2103147..2104367 (+) 1221 WP_003048956.1 S1C family serine protease Regulator
  VOI49_RS10575 spo0J 2104482..2105255 (+) 774 WP_003048958.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 42695.23 Da        Isoelectric Point: 6.3566

>NTDB_id=921044 VOI49_RS10570 WP_003048956.1 2103147..2104367(+) (htrA) [Streptococcus dysgalactiae strain lu24]
MPSMKHILKSLGILLIGFLGGLLAIFTFNATQQSSSTSHTSSATMSKMVFNNTTDTTKAVKVVQNAVVSVINYQADPSSS
LSNPYTKLFGENPAREDKDSELTVFAQGSGVIYRKDSNHAYVVTNNHVIDGAKRIEILMADGTKVVGELIGADTYSDLAV
VKISSDKIKTVAEFADSTKLNVGETAIAIGSPLGTQYANSVTKGIVSSLSRTVTLKNEDGETVSTNAIQTDAAINPGNSG
GPLINIEGQVIGINSSKISSTPSGINGNSGAVEGISFAIPSNDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQI
NIPTSITGGIVVGSVQEGMPASGKLAQYDVITEIDGKAVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKTDITLTKTTQ
DLTKKQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=921044 VOI49_RS10570 WP_003048956.1 2103147..2104367(+) (htrA) [Streptococcus dysgalactiae strain lu24]
ATGCCATCTATGAAACATATCTTAAAATCCTTAGGCATTTTACTCATTGGATTTTTAGGAGGATTGTTAGCAATTTTCAC
TTTTAATGCTACTCAACAGTCTTCCTCTACCTCACATACTAGTAGTGCGACGATGAGTAAGATGGTTTTTAATAATACTA
CTGACACAACAAAAGCGGTTAAAGTCGTCCAAAACGCAGTAGTATCAGTGATTAACTATCAAGCAGATCCTTCTTCATCT
CTTTCTAATCCTTACACAAAACTCTTTGGAGAAAATCCAGCAAGAGAAGATAAAGATTCCGAATTAACAGTTTTTGCTCA
AGGTTCTGGTGTCATTTATCGAAAAGATTCCAATCATGCCTATGTTGTGACTAACAATCATGTTATTGACGGCGCAAAAC
GAATTGAAATTCTTATGGCAGATGGAACTAAGGTAGTAGGAGAATTAATTGGTGCGGATACTTATTCTGACTTAGCTGTA
GTTAAAATTTCTTCAGATAAGATTAAAACAGTAGCTGAATTTGCAGATTCTACTAAACTTAATGTTGGAGAAACTGCTAT
TGCTATTGGTAGTCCACTGGGAACTCAATACGCAAATTCAGTTACGAAAGGAATTGTATCGAGCCTAAGTCGTACCGTTA
CCTTAAAAAACGAAGATGGAGAAACTGTTTCAACAAATGCTATCCAAACAGATGCTGCTATTAACCCCGGAAATTCTGGG
GGACCACTAATTAATATAGAAGGACAGGTTATCGGTATTAATTCAAGTAAGATTTCTTCTACTCCATCTGGTATTAATGG
GAATAGTGGAGCTGTCGAAGGAATTAGCTTTGCTATTCCATCTAATGATGTCATTAAAATCATTAAGCAATTAGAAACCA
ACGGTGAAGTCATACGACCTGCTCTTGGTATCTCTATGGTTAACCTAAATGATTTATCAACTAATGCTCTTAGTCAAATT
AATATCCCAACTAGTATCACTGGCGGCATTGTGGTTGGTTCTGTTCAAGAGGGAATGCCAGCAAGTGGTAAACTTGCCCA
GTACGATGTCATTACAGAAATTGATGGGAAAGCTGTTAATTCAATAAGTGATCTTCAAAGTAGTCTATATGGCCATGACA
TTAACGATACCATCAAGGTAACCTTTTATAGAGGGACAACCAAGAAAAAAACAGATATTACCTTAACTAAAACAACTCAG
GATTTGACCAAAAAGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(300-395)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380JYG2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

59.204

99.015

0.586
  htrA Streptococcus mitis NCTC 12261

54.054

100

0.542
  htrA Streptococcus pneumoniae Rx1

54.054

100

0.542
  htrA Streptococcus pneumoniae TIGR4

54.054

100

0.542
  htrA Streptococcus pneumoniae D39

54.054

100

0.542
  htrA Streptococcus pneumoniae R6

54.054

100

0.542
  htrA Streptococcus gordonii str. Challis substr. CH1

54.208

99.507

0.539