Detailed information NTG0919791

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: VO180_RS02715
• Genome accession: NZ_CP141826
• Coordinates: 540256..541419 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain XHA16
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 535256..546419

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VO180_RS02695 (VO180_02695)	tuaH	535624..536820 (+)	1197	WP_324636350.1	teichuronic acid biosynthesis protein TuaH	-
VO180_RS02700 (VO180_02700)	-	536953..538029 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
VO180_RS02705 (VO180_02705)	-	538128..539381 (-)	1254	WP_324636351.1	LCP family protein	-
VO180_RS02710 (VO180_02710)	-	539386..540033 (-)	648	WP_003151384.1	YigZ family protein	-
VO180_RS02715 (VO180_02715)	degS	540256..541419 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
VO180_RS02720 (VO180_02720)	degU	541496..542185 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
VO180_RS02725 (VO180_02725)	-	542283..543131 (+)	849	WP_015418336.1	DegV family protein	-
VO180_RS02730 (VO180_02730)	comFA	543239..544624 (+)	1386	WP_040238815.1	DEAD/DEAH box helicase	Machinery gene
VO180_RS02735 (VO180_02735)	-	544682..544966 (+)	285	WP_003151389.1	late competence development ComFB family protein	-
VO180_RS02740 (VO180_02740)	comFC	544972..545661 (+)	690	WP_197093073.1	phosphoribosyltransferase family protein	Machinery gene
VO180_RS02745 (VO180_02745)	-	545735..546154 (+)	420	WP_324636352.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=919791 VO180_RS02715 WP_007407484.1 540256..541419(+) (degS) [Bacillus velezensis strain XHA16]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=919791 VO180_RS02715 WP_007407484.1 540256..541419(+) (degS) [Bacillus velezensis strain XHA16]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951