Detailed information NTG0918869

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: VNN53_RS08525
• Genome accession: NZ_CP141720
• Coordinates: 1746458..1747327 (+)
• Length: 289 a.a.
• NCBI ID: WP_019293953.1
• Uniprot ID: A0AAJ2IZH0
• Organism: Lactococcus garvieae strain CAHFS22OV20.5B5
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1741458..1752327

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN53_RS08505 (VNN53_08505)	-	1741788..1742408 (+)	621	WP_019291676.1	GntR family transcriptional regulator	-
VNN53_RS08510 (VNN53_08510)	-	1742614..1743816 (+)	1203	WP_014024780.1	glycine betaine/L-proline ABC transporter ATP-binding protein	-
VNN53_RS08515 (VNN53_08515)	-	1743809..1745533 (+)	1725	WP_086582599.1	ABC transporter permease/substrate binding protein	-
VNN53_RS08520 (VNN53_08520)	budA	1745673..1746371 (+)	699	WP_165716817.1	acetolactate decarboxylase	-
VNN53_RS08525 (VNN53_08525)	dprA	1746458..1747327 (+)	870	WP_019293953.1	DNA-processing protein DprA	Machinery gene
VNN53_RS08530 (VNN53_08530)	topA	1747516..1749666 (+)	2151	WP_165716815.1	type I DNA topoisomerase	-
VNN53_RS08535 (VNN53_08535)	trmFO	1749715..1751058 (+)	1344	WP_285121914.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
VNN53_RS08540 (VNN53_08540)	-	1751132..1751353 (-)	222	WP_019292266.1	hypothetical protein	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32871.09 Da
• Isoelectric Point: 9.9003

>NTDB_id=918869 VNN53_RS08525 WP_019293953.1 1746458..1747327(+) (dprA) [Lactococcus garvieae strain CAHFS22OV20.5B5]
MIKNFEILRLKKAGMSNLGILKLIDYQRRHEAKLTLRQLARIAEVKTVPNFIESYKSQDVKRLREQYKIFPSFSILDDIY
PEWLRETYNPPALLFYRGDLKLLSLPKLGFVGSREMSKEAPRIIHKLIEELKQNFVIVSGLARGVDTSSHVAAVKQKTPT
IAVIGNGLDISYPKENRKLQEYLAAHELVLSEYLVGEQPLKFHFPERNRIIAGLSRGVVVVEAKQRSGSLITSRYALEGN
REVFAVPGDILNRNASGCNQLIQQGAAKLVTHGQDILDEFYLYEGNFFP

Nucleotide

• Length: 870 bp

>NTDB_id=918869 VNN53_RS08525 WP_019293953.1 1746458..1747327(+) (dprA) [Lactococcus garvieae strain CAHFS22OV20.5B5]
ATGATTAAAAACTTTGAAATATTACGTTTGAAAAAAGCAGGAATGTCTAATTTAGGGATTTTGAAACTGATTGATTATCA
GAGGAGGCATGAAGCAAAACTCACTCTACGCCAGTTAGCGCGGATTGCAGAGGTCAAAACTGTCCCTAATTTTATTGAGA
GTTATAAGAGTCAAGATGTGAAACGACTTCGTGAGCAATACAAAATTTTCCCCTCCTTTTCCATTTTAGATGACATTTAT
CCCGAATGGCTGAGAGAAACATATAATCCGCCTGCCCTCCTTTTTTACCGAGGAGATCTTAAATTGCTTAGTCTTCCTAA
ACTTGGGTTTGTAGGCAGTCGTGAAATGTCTAAGGAAGCACCAAGAATAATCCACAAGCTTATTGAGGAATTAAAGCAAA
ACTTTGTTATTGTGAGCGGATTAGCACGCGGTGTTGACACCTCAAGCCATGTAGCAGCTGTAAAACAAAAAACTCCAACC
ATTGCTGTCATTGGTAATGGGTTAGATATTAGTTATCCAAAAGAAAATCGTAAATTACAAGAATACTTAGCAGCACATGA
ATTAGTTTTATCAGAATACCTTGTAGGAGAGCAACCCCTCAAGTTTCATTTCCCAGAGAGAAATAGAATCATTGCTGGTC
TTTCCCGTGGAGTTGTCGTTGTGGAAGCAAAACAACGTAGTGGTAGCCTTATCACAAGTCGTTATGCTTTAGAGGGTAAT
AGAGAAGTTTTTGCTGTACCTGGAGATATTTTGAATAGAAATGCTTCTGGCTGTAATCAATTAATCCAACAAGGTGCAGC
CAAGCTTGTCACTCATGGACAAGATATTTTAGATGAATTTTATTTATATGAAGGGAATTTCTTTCCTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	63.958	97.924	0.626
dprA	Streptococcus mutans UA159	55.556	96.54	0.536
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	53.763	96.54	0.519
dprA/cilB/dalA	Streptococcus pneumoniae D39	53.763	96.54	0.519
dprA/cilB/dalA	Streptococcus pneumoniae R6	53.763	96.54	0.519
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	53.763	96.54	0.519
dprA/cilB/dalA	Streptococcus mitis SK321	53.763	96.54	0.519
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	53.047	96.54	0.512
dprA	Latilactobacillus sakei subsp. sakei 23K	39.273	95.156	0.374