Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   VNN45_RS08480 Genome accession   NZ_CP141698
Coordinates   1742338..1743207 (+) Length   289 a.a.
NCBI ID   WP_019293953.1    Uniprot ID   A0AAJ2IZH0
Organism   Lactococcus petauri strain R21-91A     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1712054..1784989 1742338..1743207 within 0


Gene organization within MGE regions


Location: 1712054..1784989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN45_RS08330 (VNN45_08330) - 1712355..1713836 (-) 1482 WP_019293976.1 glycosyl hydrolase family 18 protein -
  VNN45_RS08335 (VNN45_08335) - 1714120..1714605 (+) 486 WP_019293975.1 TspO/MBR family protein -
  VNN45_RS08340 (VNN45_08340) - 1714693..1715517 (-) 825 WP_019293974.1 Rgg/GadR/MutR family transcriptional regulator -
  VNN45_RS08345 (VNN45_08345) - 1715717..1716085 (+) 369 WP_333494066.1 ArsC/Spx/MgsR family protein -
  VNN45_RS08350 (VNN45_08350) - 1716152..1716859 (+) 708 WP_080567256.1 EAL domain-containing protein -
  VNN45_RS08355 (VNN45_08355) - 1716872..1718017 (+) 1146 WP_019293972.1 GGDEF domain-containing protein -
  VNN45_RS08360 (VNN45_08360) nagE 1718314..1720281 (+) 1968 WP_019293971.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  VNN45_RS08365 (VNN45_08365) - 1720441..1722477 (+) 2037 WP_019293970.1 copper-translocating P-type ATPase -
  VNN45_RS08370 (VNN45_08370) - 1722502..1722951 (-) 450 WP_338954921.1 GNAT family N-acetyltransferase -
  VNN45_RS08375 (VNN45_08375) - 1723112..1723438 (+) 327 WP_019293968.1 PadR family transcriptional regulator -
  VNN45_RS08380 (VNN45_08380) - 1723431..1724051 (+) 621 WP_019293967.1 DUF1700 domain-containing protein -
  VNN45_RS08385 (VNN45_08385) - 1724048..1724926 (+) 879 WP_019293966.1 DUF4097 family beta strand repeat-containing protein -
  VNN45_RS08390 (VNN45_08390) - 1724940..1725779 (+) 840 WP_019293965.1 undecaprenyl-diphosphate phosphatase -
  VNN45_RS08395 (VNN45_08395) - 1725887..1726528 (-) 642 WP_019293964.1 hypothetical protein -
  VNN45_RS08400 (VNN45_08400) - 1726715..1727287 (+) 573 WP_019293963.1 TetR/AcrR family transcriptional regulator -
  VNN45_RS08405 (VNN45_08405) - 1727307..1727666 (+) 360 WP_019293962.1 iron-sulfur cluster biosynthesis family protein -
  VNN45_RS08410 (VNN45_08410) - 1727668..1729026 (+) 1359 WP_019293961.1 FAD-dependent oxidoreductase -
  VNN45_RS08415 (VNN45_08415) - 1729154..1730308 (+) 1155 WP_019293960.1 cystathionine gamma-synthase -
  VNN45_RS08420 (VNN45_08420) - 1730418..1730966 (+) 549 WP_017369818.1 DUF6036 family nucleotidyltransferase -
  VNN45_RS08425 (VNN45_08425) - 1730967..1731248 (+) 282 WP_019293959.1 hypothetical protein -
  VNN45_RS08430 (VNN45_08430) - 1731315..1732688 (+) 1374 WP_019293958.1 M24 family metallopeptidase -
  VNN45_RS08435 (VNN45_08435) ahpC 1732953..1733516 (+) 564 WP_019293957.1 alkyl hydroperoxide reductase subunit C -
  VNN45_RS08440 (VNN45_08440) ahpF 1733575..1735104 (+) 1530 WP_019293956.1 alkyl hydroperoxide reductase subunit F -
  VNN45_RS08445 (VNN45_08445) - 1735269..1735886 (+) 618 WP_017370397.1 FMN-dependent NADH-azoreductase -
  VNN45_RS08450 (VNN45_08450) raiA 1735997..1736554 (+) 558 WP_019291678.1 ribosome-associated translation inhibitor RaiA -
  VNN45_RS08455 (VNN45_08455) - 1736605..1737441 (-) 837 WP_019291677.1 DUF368 domain-containing protein -
  VNN45_RS08460 (VNN45_08460) - 1737666..1738286 (+) 621 WP_019291676.1 GntR family transcriptional regulator -
  VNN45_RS08465 (VNN45_08465) - 1738491..1739693 (+) 1203 WP_338954930.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  VNN45_RS08470 (VNN45_08470) - 1739686..1741410 (+) 1725 WP_019293955.1 ABC transporter permease/substrate binding protein -
  VNN45_RS08475 (VNN45_08475) budA 1741553..1742251 (+) 699 WP_019293954.1 acetolactate decarboxylase -
  VNN45_RS08480 (VNN45_08480) dprA 1742338..1743207 (+) 870 WP_019293953.1 DNA-processing protein DprA Machinery gene
  VNN45_RS08485 (VNN45_08485) topA 1743396..1745546 (+) 2151 WP_029345828.1 type I DNA topoisomerase -
  VNN45_RS08490 (VNN45_08490) trmFO 1745595..1746938 (+) 1344 WP_019293951.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  VNN45_RS08495 (VNN45_08495) - 1747012..1747233 (-) 222 WP_019292266.1 hypothetical protein -
  VNN45_RS08500 (VNN45_08500) xerS 1747299..1748360 (-) 1062 WP_019293950.1 tyrosine recombinase XerS -
  VNN45_RS08505 (VNN45_08505) - 1748891..1749160 (-) 270 WP_338954933.1 hypothetical protein -
  VNN45_RS08510 (VNN45_08510) xerS 1749275..1750321 (-) 1047 WP_338954935.1 tyrosine recombinase XerS -
  VNN45_RS08515 (VNN45_08515) - 1750421..1750585 (-) 165 WP_285123159.1 hypothetical protein -
  VNN45_RS08520 (VNN45_08520) - 1750586..1752016 (-) 1431 WP_338954941.1 Y-family DNA polymerase -
  VNN45_RS08525 (VNN45_08525) - 1752504..1754390 (-) 1887 WP_338954943.1 P-loop NTPase fold protein -
  VNN45_RS08530 (VNN45_08530) - 1754483..1755967 (-) 1485 WP_338954945.1 relaxase/mobilization nuclease domain-containing protein -
  VNN45_RS08535 (VNN45_08535) mobC 1755968..1756363 (-) 396 WP_338954947.1 plasmid mobilization relaxosome protein MobC -
  VNN45_RS08540 (VNN45_08540) - 1756605..1757348 (-) 744 WP_338954949.1 hypothetical protein -
  VNN45_RS08545 (VNN45_08545) - 1757408..1757707 (-) 300 WP_338954951.1 hypothetical protein -
  VNN45_RS08550 (VNN45_08550) - 1757745..1761587 (-) 3843 WP_338954953.1 PBECR4 domain-containing protein -
  VNN45_RS08555 (VNN45_08555) - 1761709..1762551 (-) 843 WP_338954955.1 PASTA domain-containing protein -
  VNN45_RS08560 (VNN45_08560) - 1762672..1763169 (-) 498 WP_338954957.1 type III secretion system protein PrgE -
  VNN45_RS08565 (VNN45_08565) - 1763177..1764145 (-) 969 WP_338954959.1 hypothetical protein -
  VNN45_RS08570 (VNN45_08570) - 1764201..1765382 (-) 1182 WP_338954961.1 zinc ribbon domain-containing protein -
  VNN45_RS08575 (VNN45_08575) - 1765382..1765633 (-) 252 WP_338954963.1 hypothetical protein -
  VNN45_RS08580 (VNN45_08580) - 1765635..1766264 (-) 630 WP_338954965.1 hypothetical protein -
  VNN45_RS08585 (VNN45_08585) - 1766310..1768991 (-) 2682 WP_338954967.1 phage tail tip lysozyme -
  VNN45_RS08590 (VNN45_08590) - 1768996..1771362 (-) 2367 WP_338954969.1 AAA family ATPase -
  VNN45_RS08595 (VNN45_08595) - 1771310..1771669 (-) 360 WP_165719644.1 PrgI family protein -
  VNN45_RS08600 (VNN45_08600) - 1771671..1772441 (-) 771 WP_213439179.1 hypothetical protein -
  VNN45_RS08605 (VNN45_08605) - 1772469..1772906 (-) 438 WP_165719642.1 hypothetical protein -
  VNN45_RS08610 (VNN45_08610) - 1772969..1774798 (-) 1830 WP_338954974.1 type IV secretory system conjugative DNA transfer family protein -
  VNN45_RS08615 (VNN45_08615) - 1774795..1775547 (-) 753 WP_338954976.1 hypothetical protein -
  VNN45_RS08620 (VNN45_08620) - 1775544..1779074 (-) 3531 WP_338954978.1 LPXTG cell wall anchor domain-containing protein -
  VNN45_RS08625 (VNN45_08625) - 1779096..1779287 (-) 192 WP_338954980.1 hypothetical protein -
  VNN45_RS08630 (VNN45_08630) - 1779280..1779810 (-) 531 WP_338954982.1 hypothetical protein -
  VNN45_RS08635 (VNN45_08635) - 1779817..1780494 (-) 678 WP_338954984.1 class A sortase -
  VNN45_RS08640 (VNN45_08640) - 1780550..1784362 (-) 3813 WP_338954986.1 SpaA isopeptide-forming pilin-related protein -
  VNN45_RS08645 (VNN45_08645) - 1784512..1784898 (-) 387 WP_338954988.1 hypothetical protein -

Sequence

Protein


Download         Length: 289 a.a.        Molecular weight: 32871.09 Da        Isoelectric Point: 9.9003

>NTDB_id=918422 VNN45_RS08480 WP_019293953.1 1742338..1743207(+) (dprA) [Lactococcus petauri strain R21-91A]
MIKNFEILRLKKAGMSNLGILKLIDYQRRHEAKLTLRQLARIAEVKTVPNFIESYKSQDVKRLREQYKIFPSFSILDDIY
PEWLRETYNPPALLFYRGDLKLLSLPKLGFVGSREMSKEAPRIIHKLIEELKQNFVIVSGLARGVDTSSHVAAVKQKTPT
IAVIGNGLDISYPKENRKLQEYLAAHELVLSEYLVGEQPLKFHFPERNRIIAGLSRGVVVVEAKQRSGSLITSRYALEGN
REVFAVPGDILNRNASGCNQLIQQGAAKLVTHGQDILDEFYLYEGNFFP

Nucleotide


Download         Length: 870 bp        

>NTDB_id=918422 VNN45_RS08480 WP_019293953.1 1742338..1743207(+) (dprA) [Lactococcus petauri strain R21-91A]
ATGATTAAAAACTTTGAAATATTACGTTTAAAAAAAGCAGGAATGTCTAATTTAGGGATTTTGAAACTGATTGATTATCA
GAGGAGGCATGAAGCAAAACTCACTCTACGCCAGTTAGCGCGGATTGCAGAGGTCAAAACTGTCCCTAATTTTATTGAGA
GTTATAAGAGTCAAGATGTGAAACGACTTCGTGAGCAATACAAAATTTTCCCCTCCTTTTCCATTTTAGATGACATTTAT
CCCGAATGGCTGAGAGAAACATATAATCCGCCTGCCCTCCTTTTTTACCGAGGAGATCTTAAATTGCTTAGTCTTCCTAA
ACTTGGGTTTGTAGGTAGTCGTGAAATGTCTAAGGAAGCACCAAGAATAATCCACAAGCTTATTGAGGAATTAAAGCAAA
ACTTTGTTATTGTGAGCGGATTAGCACGCGGTGTTGACACCTCAAGCCATGTAGCAGCTGTAAAACAAAAAACTCCAACC
ATTGCTGTCATTGGTAATGGGTTAGATATTAGTTATCCAAAAGAAAATCGTAAATTACAAGAATACTTAGCAGCACATGA
ATTAGTTTTATCAGAATACCTTGTAGGAGAGCAACCCCTCAAGTTTCATTTCCCAGAGAGAAATAGAATCATTGCTGGTC
TTTCCCGTGGTGTTGTTGTTGTGGAAGCAAAACAACGTAGTGGTAGCCTTATCACAAGTCGTTATGCTTTAGAGGGTAAT
AGAGAAGTTTTTGCTGTACCTGGAGATATTTTGAATAGAAATGCTTCTGGCTGTAATCAATTAATCCAACAAGGTGCAGC
CAAGCTTGTCACTCATGGACAAGATATTTTAGATGAATTTTATTTATATGAAGGGAATTTCTTTCCTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(2-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Lactococcus lactis subsp. cremoris KW2

63.958

97.924

0.626
  dprA Streptococcus mutans UA159

55.556

96.54

0.536
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

53.763

96.54

0.519
  dprA/cilB/dalA Streptococcus pneumoniae D39

53.763

96.54

0.519
  dprA/cilB/dalA Streptococcus pneumoniae R6

53.763

96.54

0.519
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

53.763

96.54

0.519
  dprA/cilB/dalA Streptococcus mitis SK321

53.763

96.54

0.519
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

53.047

96.54

0.512
  dprA Latilactobacillus sakei subsp. sakei 23K

39.273

95.156

0.374