Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   U0N78_RS06225 Genome accession   NZ_CP140109
Coordinates   1266740..1267582 (+) Length   280 a.a.
NCBI ID   WP_014638936.1    Uniprot ID   A0A116MH00
Organism   Streptococcus suis strain 2022WUSS148     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1261740..1272582
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS06195 (U0N78_06195) - 1262575..1263354 (+) 780 WP_043026878.1 ribonuclease HII -
  U0N78_RS06200 (U0N78_06200) - 1263351..1264361 (+) 1011 WP_043026879.1 YdcF family protein -
  U0N78_RS06205 (U0N78_06205) trhA 1264394..1265044 (-) 651 WP_043026880.1 PAQR family membrane homeostasis protein TrhA -
  U0N78_RS06210 (U0N78_06210) - 1265034..1265585 (-) 552 WP_014638939.1 DUF1836 domain-containing protein -
  U0N78_RS06215 (U0N78_06215) - 1265682..1265993 (-) 312 WP_014638938.1 rhodanese-like domain-containing protein -
  U0N78_RS06220 (U0N78_06220) - 1266122..1266679 (+) 558 WP_014638937.1 sugar O-acetyltransferase -
  U0N78_RS06225 (U0N78_06225) dprA 1266740..1267582 (+) 843 WP_014638936.1 DNA-processing protein DprA Machinery gene
  U0N78_RS06230 (U0N78_06230) topA 1267675..1269768 (+) 2094 WP_043027054.1 type I DNA topoisomerase -
  U0N78_RS06235 (U0N78_06235) rplJ 1270283..1270777 (+) 495 WP_002936486.1 50S ribosomal protein L10 -
  U0N78_RS06240 (U0N78_06240) rplL 1270843..1271208 (+) 366 WP_002936483.1 50S ribosomal protein L7/L12 -
  U0N78_RS06245 (U0N78_06245) - 1271333..1272043 (+) 711 WP_256769133.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31347.20 Da        Isoelectric Point: 8.2214

>NTDB_id=912587 U0N78_RS06225 WP_014638936.1 1266740..1267582(+) (dprA) [Streptococcus suis strain 2022WUSS148]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKIYPKENRELQTYIGKHHLVLTEYEPDADPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=912587 U0N78_RS06225 WP_014638936.1 1266740..1267582(+) (dprA) [Streptococcus suis strain 2022WUSS148]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGAAAAAAATTGACCTTGCGAAATGTCGCTGTAGTATCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
CTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTACCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTATCCAATCTGTTCAGAAAATTATCAAAGAATTGAGCAATCGTT
TTGTCATTGTTAGTGGTTTGGCAAGAGGAATTGATACAGCAGCCCACATCGCCAGTTTGAAAAATGGAGGCCAAACCATT
GCCGTTATTGGAACAGGTTTGGATAAGATTTATCCCAAAGAAAACAGAGAATTGCAGACCTACATAGGTAAACACCATTT
AGTTTTGACTGAATATGAACCAGATGCAGACCCTCTCAAATACCATTTTCCAGAACGCAATCGCATTATAGCTGGTTTGG
TAGAAGGATTGGTAGTCTGTGAGGCAAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGCAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116MH00

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

69.643

100

0.696
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

62.857

100

0.629
  dprA/cilB/dalA Streptococcus pneumoniae D39

62.857

100

0.629
  dprA/cilB/dalA Streptococcus pneumoniae R6

62.857

100

0.629
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

62.857

100

0.629
  dprA/cilB/dalA Streptococcus mitis SK321

62.857

100

0.629
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

62.857

100

0.629
  dprA Lactococcus lactis subsp. cremoris KW2

60

100

0.6
  dprA Legionella pneumophila strain ERS1305867

42.105

88.214

0.371
  dprA Bacillus subtilis subsp. subtilis str. 168

51.244

71.786

0.368