Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   U0N78_RS03705 Genome accession   NZ_CP140109
Coordinates   751965..752669 (+) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain 2022WUSS148     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 746965..757669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS03685 (U0N78_03685) - 748773..749432 (-) 660 WP_170238281.1 amino acid ABC transporter permease -
  U0N78_RS03690 (U0N78_03690) - 749447..750145 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  U0N78_RS03695 (U0N78_03695) - 750160..750999 (-) 840 WP_170238280.1 transporter substrate-binding domain-containing protein -
  U0N78_RS03700 (U0N78_03700) - 751010..751771 (-) 762 WP_170238279.1 amino acid ABC transporter ATP-binding protein -
  U0N78_RS03705 (U0N78_03705) micA 751965..752669 (+) 705 WP_004298854.1 response regulator YycF Regulator
  U0N78_RS03710 (U0N78_03710) micB 752662..754011 (+) 1350 WP_170238278.1 cell wall metabolism sensor histidine kinase VicK Regulator
  U0N78_RS03715 (U0N78_03715) vicX 754018..754821 (+) 804 WP_024378370.1 MBL fold metallo-hydrolase Regulator
  U0N78_RS03720 (U0N78_03720) vga(F) 755352..756737 (+) 1386 WP_032499500.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=912576 U0N78_RS03705 WP_004298854.1 751965..752669(+) (micA) [Streptococcus suis strain 2022WUSS148]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=912576 U0N78_RS03705 WP_004298854.1 751965..752669(+) (micA) [Streptococcus suis strain 2022WUSS148]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAGATTGAAGATACAC
CAAGCCGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376