Detailed information NTG0091208

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: L6419_RS09975
• Genome accession: NZ_AP025332
• Coordinates: 2113214..2114389 (+)
• Length: 391 a.a.
• NCBI ID: WP_155963394.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-184
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2108214..2119389

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L6419_RS09935 (GUT184_19250)	-	2108494..2109738 (+)	1245	WP_155963396.1	replication initiation factor domain-containing protein	-
L6419_RS09940 (GUT184_19260)	-	2109801..2110139 (+)	339	WP_029186211.1	DUF771 domain-containing protein	-
L6419_RS09945 (GUT184_19270)	-	2110202..2111323 (+)	1122	WP_014638877.1	site-specific integrase	-
L6419_RS09965 (GUT184_19280)	-	2111834..2112518 (-)	685	Protein_1924	YoaK family protein	-
L6419_RS09970 (GUT184_19290)	rlmH	2112543..2113022 (-)	480	WP_024531474.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
L6419_RS09975 (GUT184_19300)	htrA	2113214..2114389 (+)	1176	WP_155963394.1	S1C family serine protease	Regulator
L6419_RS09980 (GUT184_19310)	spo0J	2114450..2115208 (+)	759	WP_237375448.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 41627.07 Da
• Isoelectric Point: 8.9096

>NTDB_id=91208 L6419_RS09975 WP_155963394.1 2113214..2114389(+) (htrA) [Streptococcus ruminantium strain GUT-184]
MKKYLKFTILFAVGLLGGFVGSFMTASFFQPQAQQQANSTITNVSKVQYNNETSTTKAVEKVQNAVVSVINYQKSANNSL
RSIFGNIDTPDEPVVAGEGSGVIYKKDDKYAYVVTNTHVINNAEKIDILLTSGEKVRGELVGSDTYSDIAVIRIPADKVT
TVAEFANSNTIKVGEPAIAIGSPLGSVYANTVTQGIISSLSRTITSQSEDGQTISTNAIQTDAAINPGNSGGPLINIKGQ
VVGINSSKKSTSRSGVAIEGMGFAIPANDVVAIINQIEKNGKVIRPALGFQLVNLTDLSTGQLEKAGLSDTKLTSGVVVV
STQKGLPADGKLETFDVITEINGEAVQNKSDLQSILYKHKIGDTIKVTYYRNNKKQTVDIKLTHSTEQLSQ

Nucleotide

• Length: 1176 bp

>NTDB_id=91208 L6419_RS09975 WP_155963394.1 2113214..2114389(+) (htrA) [Streptococcus ruminantium strain GUT-184]
ATGAAAAAATATTTGAAATTTACTATTCTATTTGCTGTTGGTCTTTTGGGTGGTTTTGTTGGTTCTTTCATGACTGCCTC
TTTCTTTCAACCACAAGCACAACAACAGGCAAATTCTACTATTACAAATGTCAGCAAGGTGCAATACAATAATGAGACCT
CTACTACAAAAGCAGTAGAAAAGGTGCAAAATGCTGTTGTTTCAGTAATTAACTATCAAAAATCAGCAAACAATAGCCTA
CGCTCCATCTTCGGAAATATTGATACACCGGATGAACCTGTAGTAGCTGGAGAAGGTTCGGGTGTTATCTATAAAAAAGA
CGATAAATATGCCTACGTTGTTACCAATACGCATGTTATCAATAACGCAGAAAAAATAGATATTCTTCTAACTTCAGGAG
AAAAGGTCAGAGGAGAACTTGTTGGTTCTGACACTTATTCTGACATAGCTGTAATAAGGATTCCTGCTGATAAGGTCACT
ACTGTTGCCGAATTTGCTAACTCCAATACTATCAAGGTCGGTGAACCTGCTATCGCTATCGGTAGCCCACTTGGTAGTGT
CTATGCTAATACTGTTACACAAGGTATTATTTCTAGTTTGAGTAGAACTATCACCTCACAATCAGAAGATGGACAAACTA
TCTCTACCAACGCTATCCAAACAGATGCAGCCATTAACCCAGGTAATTCAGGTGGTCCACTGATAAATATTAAAGGACAA
GTTGTGGGGATCAATTCAAGTAAAAAGAGTACATCGAGATCCGGTGTTGCTATAGAAGGGATGGGCTTTGCTATTCCTGC
TAATGATGTAGTAGCTATTATCAATCAAATTGAGAAAAATGGTAAAGTTATCCGACCTGCTCTCGGTTTCCAACTAGTCA
ATTTGACAGATTTGTCAACTGGACAATTAGAAAAAGCTGGATTATCAGATACCAAATTAACATCTGGTGTTGTAGTTGTT
TCAACGCAGAAGGGGTTACCTGCTGATGGAAAACTTGAAACCTTTGATGTTATCACTGAGATTAACGGTGAAGCTGTTCA
AAATAAGAGCGATCTTCAAAGTATCCTCTACAAGCATAAAATTGGTGATACGATTAAGGTTACCTACTATCGTAACAATA
AAAAGCAAACAGTTGACATCAAGTTGACACATTCTACGGAGCAACTCAGTCAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (99-244)

• PDZ domain (PDZ_2) (286-382)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.494	100	0.601
htrA	Streptococcus gordonii str. Challis substr. CH1	59.184	100	0.593
htrA	Streptococcus pneumoniae Rx1	55.784	99.488	0.555
htrA	Streptococcus pneumoniae D39	55.784	99.488	0.555
htrA	Streptococcus pneumoniae R6	55.784	99.488	0.555
htrA	Streptococcus pneumoniae TIGR4	55.784	99.488	0.555
htrA	Streptococcus mitis NCTC 12261	55.784	99.488	0.555