Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   U0036_RS05200 Genome accession   NZ_CP139967
Coordinates   1126553..1128988 (+) Length   811 a.a.
NCBI ID   WP_063238421.1    Uniprot ID   A0A375GAA0
Organism   Cupriavidus oxalaticus strain HAMBI_2164     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1121553..1133988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0036_RS05180 (U0036_05185) - 1122371..1123477 (-) 1107 WP_063238417.1 hypothetical protein -
  U0036_RS05185 (U0036_05190) - 1123625..1124875 (+) 1251 WP_063238418.1 lipoprotein-releasing ABC transporter permease subunit -
  U0036_RS05190 (U0036_05195) lolD 1124868..1125608 (+) 741 WP_063238419.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  U0036_RS05195 (U0036_05200) - 1125630..1126481 (+) 852 WP_063238420.1 TatD family hydrolase -
  U0036_RS05200 (U0036_05205) comA 1126553..1128988 (+) 2436 WP_063238421.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  U0036_RS05205 (U0036_05210) - 1128985..1129935 (-) 951 WP_063238422.1 MurR/RpiR family transcriptional regulator -
  U0036_RS05210 (U0036_05215) edd 1130190..1132085 (+) 1896 WP_063238423.1 phosphogluconate dehydratase -
  U0036_RS05215 (U0036_05220) - 1132140..1132625 (+) 486 WP_063238424.1 gluconokinase -

Sequence

Protein


Download         Length: 811 a.a.        Molecular weight: 86004.05 Da        Isoelectric Point: 10.3941

>NTDB_id=912062 U0036_RS05200 WP_063238421.1 1126553..1128988(+) (comA) [Cupriavidus oxalaticus strain HAMBI_2164]
MRVVVLAFVAGCWVLQQQATLPRQDVVRMAAAGLALAGIAMLLRGRALRAAWRGLVLAAVAAVAVGAAFCWAAWRADMRL
REWLPASLESRDFDVQGVVSGLPSESAGGVRFAFTVGKTVPDGPDEPWLLPGRLLLHWRDAPPDLYPGQRYTLTIRLRRP
RGLANPFGFDYAYWLLAQGYGATGYVRRAHGPPQDATRERLAWRIEAWRAAVRDHLRAALPADARYGPVLIALVIGDQRG
IDTEDWQLFRRTGISHLVSISGLHITMIAGMAGSFAGLLWRHSFGLGRRLRRPLPLWLPARHAALVTAVAGAMTYGLLAG
MQVPALRTVAMLCVAALAVWSGRAPPASVVLACAALAALLLDPWAVMSPGFWLSFGAVAVIFYAARSGHGAPETRWQRMC
ATLAAAARTQWAVTAGLVPLTLLLFQQVSVVSPLANAIAIPVVSLLVTPLSLAAAAVPATLAAPVLAVAHQAMVWLAALL
GWLSSLPWAMWEAPVSGPLPLLLALLGIALLLAPPAGAAVRLHGGLLVLPLVLARGPPVAHGEFRAVMLDVGQGTAVLVQ
TRAHALLYDTGPAYASGGSAGAQVVVPVLRGLGLGRLDQLMVSHEDADHAGGVADVSAAVAVAARSTGAPPDHALLGPPA
SGWAPCAAGQQWDWDGVRFTVLHPLPSQSQQAAIASNARSCVLSVATARHRLLLTGDIGVAEERALIDRLSPDALHADVM
VVAHHGSGTSSGVAWLEAVRPGAAVFQLGYANRYRHPRADVWERYGRAGIARYRSDETGAVTMATAPAGYTLSVFRQAEP
RYWRDRPDAPR

Nucleotide


Download         Length: 2436 bp        

>NTDB_id=912062 U0036_RS05200 WP_063238421.1 1126553..1128988(+) (comA) [Cupriavidus oxalaticus strain HAMBI_2164]
GTGCGCGTGGTCGTGTTGGCGTTCGTCGCGGGATGCTGGGTGCTGCAGCAGCAGGCAACGCTGCCGCGGCAGGACGTCGT
GCGCATGGCCGCTGCCGGCCTGGCGCTGGCGGGCATCGCGATGCTGCTGCGTGGCAGGGCCCTGCGTGCCGCATGGCGCG
GACTGGTGCTGGCCGCCGTGGCCGCGGTGGCCGTTGGCGCCGCGTTCTGCTGGGCGGCATGGCGCGCCGATATGCGCTTG
CGGGAGTGGTTGCCTGCATCGCTCGAATCGCGCGATTTCGACGTGCAGGGTGTGGTTTCCGGATTGCCGTCGGAATCAGC
GGGCGGCGTCCGCTTTGCCTTCACCGTCGGGAAGACCGTACCGGATGGGCCGGACGAACCATGGTTGTTGCCCGGCCGGC
TGCTTCTCCACTGGCGCGACGCGCCGCCTGACCTGTACCCCGGCCAGCGCTACACCCTGACCATACGCCTGCGGCGCCCG
CGCGGACTGGCCAATCCCTTCGGCTTCGACTATGCCTATTGGCTGCTGGCGCAGGGTTATGGCGCGACGGGTTACGTACG
ACGCGCGCATGGTCCGCCCCAGGATGCAACGCGGGAACGGCTCGCATGGCGCATCGAAGCGTGGCGCGCGGCAGTGCGCG
ATCACCTGCGCGCGGCGTTGCCGGCTGATGCGCGCTATGGCCCGGTGCTGATTGCGCTGGTGATCGGCGACCAACGCGGC
ATCGATACGGAAGACTGGCAGTTGTTCCGGCGTACCGGCATCAGCCACCTGGTCAGCATTTCAGGCTTGCATATCACCAT
GATCGCTGGCATGGCGGGGTCGTTCGCCGGCCTGCTGTGGCGGCATTCGTTCGGGCTGGGGCGCAGGCTGCGCCGGCCGC
TGCCCCTGTGGCTGCCGGCCAGGCACGCGGCCCTGGTGACGGCGGTAGCCGGTGCGATGACATACGGACTGCTGGCCGGG
ATGCAGGTGCCCGCGTTGCGCACGGTGGCGATGCTATGCGTGGCCGCGCTGGCGGTATGGAGTGGGCGCGCACCGCCGGC
GTCGGTGGTGCTGGCCTGCGCGGCACTGGCGGCATTGCTGCTGGATCCGTGGGCGGTGATGTCGCCGGGCTTCTGGCTGT
CTTTTGGCGCGGTGGCGGTGATTTTCTACGCTGCCCGGTCCGGGCATGGCGCGCCGGAAACTCGCTGGCAACGCATGTGT
GCCACGCTTGCCGCCGCGGCGCGCACGCAATGGGCGGTGACAGCCGGGCTGGTGCCGCTGACGCTGTTGCTGTTCCAGCA
GGTGTCGGTGGTGTCGCCGCTCGCCAATGCGATCGCGATCCCGGTGGTCAGCCTGCTGGTGACGCCGCTGTCGCTGGCCG
CCGCTGCCGTGCCGGCGACGCTGGCCGCGCCGGTGCTGGCCGTCGCGCATCAGGCCATGGTGTGGCTGGCCGCTTTGCTG
GGCTGGCTTTCCAGTCTGCCGTGGGCCATGTGGGAGGCGCCGGTATCGGGGCCGTTGCCGTTGCTGCTCGCCTTGCTCGG
GATCGCGCTGTTGCTGGCGCCGCCCGCCGGTGCCGCGGTGCGCCTGCATGGCGGCCTGCTGGTGTTGCCGCTCGTATTGG
CGCGCGGCCCGCCGGTGGCGCATGGCGAGTTCCGTGCGGTGATGCTCGACGTGGGGCAGGGGACCGCTGTGCTGGTGCAG
ACGCGTGCGCATGCGTTGCTGTACGACACGGGCCCTGCCTATGCATCGGGCGGCAGCGCGGGTGCGCAAGTGGTGGTGCC
GGTGCTGCGCGGCCTGGGCCTCGGCCGGCTCGACCAGCTGATGGTGAGCCATGAAGACGCGGACCATGCCGGTGGCGTGG
CGGACGTGTCGGCGGCGGTGGCCGTGGCGGCGCGCAGTACCGGCGCGCCGCCGGACCATGCCTTGCTTGGGCCGCCAGCA
TCCGGCTGGGCGCCCTGCGCGGCCGGGCAGCAATGGGACTGGGACGGCGTGCGTTTCACGGTGCTGCATCCGCTGCCATC
GCAGTCGCAACAGGCGGCGATCGCCAGCAACGCCCGTAGCTGCGTGCTGAGCGTGGCGACCGCGCGGCATCGCCTGTTGC
TGACCGGCGATATCGGCGTGGCCGAAGAGCGCGCGCTGATCGACCGGCTGTCGCCCGATGCGCTGCATGCCGACGTGATG
GTGGTGGCGCACCATGGCAGCGGCACGTCTTCCGGTGTCGCGTGGCTGGAAGCGGTGCGGCCCGGGGCCGCGGTATTCCA
GCTGGGCTATGCCAACCGCTACCGCCATCCGCGCGCCGACGTGTGGGAGCGTTATGGGCGCGCCGGCATTGCCCGCTACC
GCAGCGACGAAACCGGCGCGGTGACCATGGCCACCGCGCCGGCGGGTTATACGCTGTCGGTGTTCCGGCAGGCTGAGCCG
CGCTACTGGCGCGACCGGCCGGATGCGCCGCGCTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(550-745)

Competence protein (Competence)

(233-513)

Domain of unknown function (DUF4131) (DUF4131)

(30-189)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A375GAA0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

47.387

100

0.492