Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   L6419_RS00805 Genome accession   NZ_AP025332
Coordinates   127501..127794 (+) Length   97 a.a.
NCBI ID   WP_237375494.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 122501..132794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS00775 (GUT184_01220) - 123431..123799 (+) 369 WP_155962601.1 DUF1033 family protein -
  L6419_RS00780 (GUT184_01230) - 123837..124787 (-) 951 WP_237375492.1 S66 family peptidase -
  L6419_RS00785 (GUT184_01240) comYA 124949..125899 (+) 951 WP_155962599.1 competence type IV pilus ATPase ComGA Machinery gene
  L6419_RS00790 (GUT184_01250) comYB 125820..126851 (+) 1032 WP_272877595.1 competence type IV pilus assembly protein ComGB Machinery gene
  L6419_RS00795 (GUT184_01260) comYC 126848..127129 (+) 282 WP_024532254.1 competence type IV pilus major pilin ComGC Machinery gene
  L6419_RS00800 (GUT184_01270) comGD 127116..127529 (+) 414 WP_024532253.1 competence type IV pilus minor pilin ComGD -
  L6419_RS00805 (GUT184_01280) comYE 127501..127794 (+) 294 WP_237375494.1 competence type IV pilus minor pilin ComGE Machinery gene
  L6419_RS00810 (GUT184_01290) comGF/cglF 127781..128215 (+) 435 WP_024532251.1 competence type IV pilus minor pilin ComGF Machinery gene
  L6419_RS00815 (GUT184_01300) comGG 128193..128606 (+) 414 WP_156011187.1 competence type IV pilus minor pilin ComGG -
  L6419_RS00820 (GUT184_01310) comYH 128611..129564 (+) 954 WP_237375496.1 class I SAM-dependent methyltransferase Machinery gene
  L6419_RS00825 (GUT184_01320) - 129614..130801 (+) 1188 WP_237375497.1 acetate kinase -
  L6419_RS00830 (GUT184_01330) - 131106..131660 (+) 555 WP_024532247.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10928.89 Da        Isoelectric Point: 10.4805

>NTDB_id=91169 L6419_RS00805 WP_237375494.1 127501..127794(+) (comYE) [Streptococcus ruminantium strain GUT-184]
MVVIKNQKNKAYVLLESLVALTVFVAICSLLLSAITTGRRRQAWELKQQEILNLAQMAVQTKQHHLVLNGVEVTVQRSSN
QLVVFHEGKEVLHIAKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=91169 L6419_RS00805 WP_237375494.1 127501..127794(+) (comYE) [Streptococcus ruminantium strain GUT-184]
GTGGTCGTTATAAAAAATCAGAAGAATAAGGCCTATGTTTTGCTAGAAAGTTTGGTAGCATTGACGGTCTTTGTTGCTAT
TTGTAGCTTGCTTCTATCAGCTATAACTACTGGCCGGAGGCGTCAGGCTTGGGAATTAAAACAACAGGAAATTCTCAATC
TGGCTCAGATGGCTGTGCAGACCAAGCAACATCATTTGGTACTCAATGGTGTGGAGGTGACTGTACAACGGAGTTCAAAT
CAATTAGTCGTTTTTCACGAAGGGAAGGAGGTTTTGCACATTGCTAAAAACTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

52.083

98.969

0.515
  comYE Streptococcus mutans UA159

52.083

98.969

0.515
  comGE/cglE Streptococcus mitis SK321

41.758

93.814

0.392
  comGE/cglE Streptococcus mitis NCTC 12261

41.758

93.814

0.392
  comGE/cglE Streptococcus pneumoniae Rx1

40.659

93.814

0.381
  comGE/cglE Streptococcus pneumoniae D39

40.659

93.814

0.381
  comGE/cglE Streptococcus pneumoniae R6

40.659

93.814

0.381
  comGE/cglE Streptococcus pneumoniae TIGR4

40.659

93.814

0.381

Multiple sequence alignment