Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   U0450_RS00610 Genome accession   NZ_CP139863
Coordinates   127340..127990 (-) Length   216 a.a.
NCBI ID   WP_050210310.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P2112     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 122340..132990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS00590 - 122945..124126 (-) 1182 WP_000655935.1 membrane protein -
  U0450_RS00595 - 124130..124717 (-) 588 WP_050210313.1 ATP-binding cassette domain-containing protein -
  U0450_RS00600 - 124749..124937 (-) 189 WP_050210312.1 hypothetical protein -
  U0450_RS00605 comEC/celB 125116..127356 (-) 2241 WP_050210311.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  U0450_RS00610 comEA/celA/cilE 127340..127990 (-) 651 WP_050210310.1 helix-hairpin-helix domain-containing protein Machinery gene
  U0450_RS00615 - 128058..128627 (-) 570 WP_000443775.1 GNAT family N-acetyltransferase -
  U0450_RS00620 ald 128804..129915 (+) 1112 Protein_124 alanine dehydrogenase -
  U0450_RS00625 - 130216..130542 (-) 327 Protein_125 TfoX/Sxy family protein -
  U0450_RS00630 - 130545..131045 (-) 501 WP_000566988.1 GNAT family N-acetyltransferase -
  U0450_RS00635 - 131225..132193 (-) 969 WP_000658183.1 PhoH family protein -
  U0450_RS00640 - 132279..132494 (-) 216 WP_001232081.1 YozE family protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23251.61 Da        Isoelectric Point: 5.5171

>NTDB_id=911535 U0450_RS00610 WP_050210310.1 127340..127990(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain 15P2112]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLLVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGTKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=911535 U0450_RS00610 WP_050210310.1 127340..127990(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain 15P2112]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCTTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAGCTTAAACAGGTTAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATAGACCATCGTGAGGCAAATGG
GAAATTCAAGTCGATTGATGAACTCAAGAAGGTCTCTGGCATTGGTACTAAGACCATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

97.222

100

0.972
  comEA/celA/cilE Streptococcus pneumoniae D39

97.222

100

0.972
  comEA/celA/cilE Streptococcus pneumoniae R6

97.222

100

0.972
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.37

100

0.954
  comEA/celA/cilE Streptococcus mitis SK321

91.204

100

0.912
  comEA Lactococcus lactis subsp. cremoris KW2

44.053

100

0.463
  comEA Latilactobacillus sakei subsp. sakei 23K

34.335

100

0.37
  comEA Bacillus subtilis subsp. subtilis str. 168

42.105

87.963

0.37