Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   TM2_RS05725 Genome accession   NZ_AP025262
Coordinates   1141468..1142133 (+) Length   221 a.a.
NCBI ID   WP_008348474.1    Uniprot ID   A0A9X0KA21
Organism   Bacillus altitudinis strain TM2     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1136468..1147133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TM2_RS05695 (TM2_10630) - 1136800..1137879 (+) 1080 WP_007499018.1 ABC transporter ATP-binding protein -
  TM2_RS05700 (TM2_10640) - 1137881..1138798 (+) 918 WP_024720064.1 ABC transporter ATP-binding protein -
  TM2_RS05705 - 1138904..1139191 (+) 288 WP_116306716.1 hypothetical protein -
  TM2_RS05710 (TM2_10660) - 1139330..1139908 (+) 579 WP_057079699.1 GNAT family N-acetyltransferase -
  TM2_RS05715 (TM2_10670) spxA 1140102..1140497 (+) 396 WP_003211421.1 transcriptional regulator SpxA -
  TM2_RS05720 (TM2_10680) - 1140538..1141203 (-) 666 WP_048003215.1 TerC family protein -
  TM2_RS05725 (TM2_10690) mecA 1141468..1142133 (+) 666 WP_008348474.1 adaptor protein MecA Regulator
  TM2_RS05730 (TM2_10700) cls 1142219..1143739 (+) 1521 WP_236810376.1 cardiolipin synthase -
  TM2_RS05735 (TM2_10710) - 1143799..1145061 (+) 1263 WP_236810377.1 competence protein CoiA -
  TM2_RS05740 (TM2_10720) pepF 1145276..1147102 (+) 1827 WP_282706805.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 26471.24 Da        Isoelectric Point: 4.0153

>NTDB_id=90751 TM2_RS05725 WP_008348474.1 1141468..1142133(+) (mecA) [Bacillus altitudinis strain TM2]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIVVTKAQL
SKDGQKLELPIPEDKKDQTDEESLDALLDDFHKEEQDQEDHNEKDKKLQLQFVLKMDDFEDLIALSQLNMQDFTTSLYSF
ENRYYLYVDFHEDLSDEQVENKLSILLEYAHESVVSIYRLQEYGQLIVKENALETIQQHFS

Nucleotide


Download         Length: 666 bp        

>NTDB_id=90751 TM2_RS05725 WP_008348474.1 1141468..1142133(+) (mecA) [Bacillus altitudinis strain TM2]
ATGGAAATCGAAAGAATAAATGAACATACAGTCAAATTTTATATTTCCTACGGTGATATTGAAGATCGCGGTTTTGACCG
TGAAGAGATTTGGTATAATCGTGAGCGCAGTGAAGAGCTGTTCTGGGAAGTGATGGACGAAGTGCACGAAGAAGAAGAAT
TTGCAGTAGAGGGACCACTTTGGATTCAAGTACAGGCACTTGATAAAGGTCTTGAAATTGTCGTGACAAAAGCCCAACTT
TCTAAAGATGGACAAAAGCTCGAATTGCCGATTCCAGAAGATAAAAAAGATCAAACAGATGAAGAAAGTTTAGATGCTCT
GCTTGATGATTTTCATAAAGAAGAGCAAGATCAAGAAGATCATAATGAGAAGGACAAAAAACTTCAACTTCAGTTCGTAT
TAAAAATGGATGACTTTGAAGATTTGATTGCACTTTCTCAATTAAATATGCAGGATTTTACGACAAGTTTATATTCGTTT
GAAAACCGTTATTATCTATATGTTGACTTCCACGAGGATTTGTCAGATGAGCAGGTGGAGAATAAGCTTAGTATTCTGCT
TGAATATGCTCATGAATCAGTGGTCAGCATCTACAGACTGCAAGAATACGGTCAGCTGATTGTCAAAGAGAATGCGCTTG
AAACGATTCAACAGCACTTCTCGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

76.923

100

0.769

Multiple sequence alignment