Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   LPC25_RS02510 Genome accession   NZ_AP025176
Coordinates   544808..545377 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TPS5614     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 539808..550377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPC25_RS02485 (TPS5614TP_04620) cysE 541021..541668 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  LPC25_RS02490 (TPS5614TP_04630) cysS 541652..543052 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  LPC25_RS02495 (TPS5614TP_04640) - 543045..543449 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  LPC25_RS02500 (TPS5614TP_04650) rlmB 543457..544203 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  LPC25_RS02505 (TPS5614TP_04660) - 544203..544727 (+) 525 WP_000664732.1 NYN domain-containing protein -
  LPC25_RS02510 (TPS5614TP_04670) sigH 544808..545377 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  LPC25_RS02515 rpmG 545492..545635 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  LPC25_RS02520 (TPS5614TP_04680) secE 545691..545873 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  LPC25_RS02525 (TPS5614TP_04690) nusG 545886..546434 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  LPC25_RS02530 (TPS5614TP_04700) rplK 546615..547037 (+) 423 WP_001085795.1 50S ribosomal protein L11 -
  LPC25_RS02535 (TPS5614TP_04710) rplA 547245..547937 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  LPC25_RS02540 (TPS5614TP_04720) rplJ 548209..548709 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  LPC25_RS02545 (TPS5614TP_04730) rplL 548752..549120 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  LPC25_RS02550 (TPS5614TP_04740) - 549295..549903 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=90265 LPC25_RS02510 WP_000872873.1 544808..545377(+) (sigH) [Staphylococcus aureus strain TPS5614]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=90265 LPC25_RS02510 WP_000872873.1 544808..545377(+) (sigH) [Staphylococcus aureus strain TPS5614]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAACGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment