Detailed information NTG0902394

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SE933_RS02665
• Genome accession: NZ_CP138370
• Coordinates: 468264..469493 (-)
• Length: 409 a.a.
• NCBI ID: WP_000728356.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SagR40
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 463264..474493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE933_RS02640 (SE933_02640)	-	463374..463571 (-)	198	WP_000285199.1	DUF951 domain-containing protein	-
SE933_RS02645 (SE933_02645)	-	463581..464474 (-)	894	WP_000987448.1	diacylglycerol kinase family protein	-
SE933_RS02650 (SE933_02650)	dnaN	464532..465668 (-)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
SE933_RS02655 (SE933_02655)	dnaA	465823..467184 (-)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
SE933_RS02660 (SE933_02660)	spo0J	467393..468166 (-)	774	WP_000456088.1	ParB/RepB/Spo0J family partition protein	Regulator
SE933_RS02665 (SE933_02665)	htrA	468264..469493 (-)	1230	WP_000728356.1	S1C family serine protease	Regulator
SE933_RS02670 (SE933_02670)	rlmH	469694..470173 (+)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SE933_RS02690 (SE933_02690)	-	470754..473333 (-)	2580	WP_000154432.1	YfhO family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43104.56 Da
• Isoelectric Point: 9.5271

>NTDB_id=902394 SE933_RS02665 WP_000728356.1 468264..469493(-) (htrA) [Streptococcus agalactiae strain SagR40]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTITIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=902394 SE933_RS02665 WP_000728356.1 468264..469493(-) (htrA) [Streptococcus agalactiae strain SagR40]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTACCGTGGTGAAAATAAACAAACAATCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.104	96.088	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.533	97.311	0.55
htrA	Streptococcus pneumoniae TIGR4	55.037	99.511	0.548
htrA	Streptococcus pneumoniae Rx1	55.037	99.511	0.548
htrA	Streptococcus pneumoniae D39	55.037	99.511	0.548
htrA	Streptococcus pneumoniae R6	55.037	99.511	0.548