Detailed information NTG0899422

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: R6U80_RS11915
• Genome accession: NZ_CP137623
• Coordinates: 2387557..2388630 (-)
• Length: 357 a.a.
• NCBI ID: WP_081041295.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain NCK401
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2382557..2393630

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6U80_RS11870 (R6U80_11870)	-	2382695..2383504 (-)	810	WP_014570791.1	metal ABC transporter permease	-
R6U80_RS11875 (R6U80_11875)	-	2383497..2384234 (-)	738	WP_012898617.1	metal ABC transporter ATP-binding protein	-
R6U80_RS11880 (R6U80_11880)	-	2384411..2385253 (-)	843	WP_015427160.1	metal ABC transporter substrate-binding protein	-
R6U80_RS11885 (R6U80_11885)	-	2385250..2385687 (-)	438	WP_003129992.1	zinc-dependent MarR family transcriptional regulator	-
R6U80_RS11890 (R6U80_11890)	comGG	2385769..2386053 (-)	285	WP_025017139.1	competence type IV pilus minor pilin ComGG	Machinery gene
R6U80_RS11895 (R6U80_11895)	comGF	2386092..2386538 (-)	447	WP_029344525.1	competence type IV pilus minor pilin ComGF	Machinery gene
R6U80_RS11900 (R6U80_11900)	comGE	2386501..2386797 (-)	297	WP_010906316.1	competence type IV pilus minor pilin ComGE	Machinery gene
R6U80_RS11905 (R6U80_11905)	comGD	2386769..2387167 (-)	399	WP_230315852.1	competence type IV pilus minor pilin ComGD	Machinery gene
R6U80_RS11910 (R6U80_11910)	comGC	2387160..2387543 (-)	384	WP_313791889.1	competence type IV pilus major pilin ComGC	Machinery gene
R6U80_RS11915 (R6U80_11915)	comGB	2387557..2388630 (-)	1074	WP_081041295.1	competence type IV pilus assembly protein ComGB	Machinery gene
R6U80_RS11920 (R6U80_11920)	comGA	2388524..2389462 (-)	939	WP_031561106.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 40339.52 Da
• Isoelectric Point: 10.3001

>NTDB_id=899422 R6U80_RS11915 WP_081041295.1 2387557..2388630(-) (comGB) [Lactococcus lactis strain NCK401]
MSLGHQKIGIKKLISYLQMDISHLLKPKGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQALSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLVGIMWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFSEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEHFFTKID
RLMQLIQPLVFIFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide

• Length: 1074 bp

>NTDB_id=899422 R6U80_RS11915 WP_081041295.1 2387557..2388630(-) (comGB) [Lactococcus lactis strain NCK401]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTACTGAAGCC
AAAAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTAAAAATGAAAGAAGGTCTCGCT
TCTGGTCAAGCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAGGT
GCATGGTAACTTGTCAGGGACGATGCAATTAGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGGTTGGAATTATGTGGGGCTTAAAAAATTATTTACTACCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTTGAA
TTACGTCAAATTATTAACTTGATGAAAAAACAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCATTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACATTTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTCGTAGCATTGATGATTATTTTGCTATATGCAGCCATGTTACT
CCCCATCTATTCAAATATGGGTTCTGGAATATAG

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (41-159)

• Type II secretion system (T2SS), protein F (T2SSF) (227-348)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Lactococcus lactis subsp. cremoris KW2	83.284	95.518	0.796
comYB	Streptococcus gordonii str. Challis substr. CH1	53.959	95.518	0.515
comYB	Streptococcus mutans UA140	53.666	95.518	0.513
comYB	Streptococcus mutans UA159	53.372	95.518	0.51
comGB/cglB	Streptococcus mitis SK321	51.343	93.838	0.482
comGB/cglB	Streptococcus pneumoniae TIGR4	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae Rx1	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae D39	51.045	93.838	0.479
comGB/cglB	Streptococcus pneumoniae R6	51.045	93.838	0.479
comGB/cglB	Streptococcus mitis NCTC 12261	50.448	93.838	0.473