Detailed information NTG0896220

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: R4701_RS09935
• Genome accession: NZ_CP137114
• Coordinates: 1923874..1924722 (+)
• Length: 282 a.a.
• NCBI ID: WP_033705344.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 15P3054
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1918874..1929722

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4701_RS09910	-	1919587..1920294 (+)	708	WP_000638501.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
R4701_RS09915	-	1920299..1921321 (+)	1023	WP_000609892.1	ribitol-5-phosphate dehydrogenase	-
R4701_RS09920	licA	1921338..1922207 (+)	870	WP_000411203.1	choline kinase LicA	-
R4701_RS09925	-	1922197..1923075 (+)	879	WP_000837609.1	DMT family transporter	-
R4701_RS09930	-	1923087..1923776 (+)	690	WP_000643965.1	sugar phosphate nucleotidyltransferase	-
R4701_RS09935	dprA/cilB/dalA	1923874..1924722 (+)	849	WP_033705344.1	DNA-processing protein DprA	Machinery gene
R4701_RS09940	-	1925561..1926604 (+)	1044	WP_001812957.1	TIGR00341 family protein	-
R4701_RS09945	topA	1926771..1928858 (+)	2088	WP_000179645.1	type I DNA topoisomerase	-
R4701_RS09950	-	1929079..1929438 (+)	360	WP_001220355.1	YbaN family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31120.76 Da
• Isoelectric Point: 5.2061

>NTDB_id=896220 R4701_RS09935 WP_033705344.1 1923874..1924722(+) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 15P3054]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=896220 R4701_RS09935 WP_033705344.1 1923874..1924722(+) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 15P3054]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTTCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGATAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.456	100	0.376