Detailed information NTG0896106

Bioinformatically predicted

Overview

• Name: comGB/cglB
• Type: Machinery gene
• Locus tag: R4707_RS04715
• Genome accession: NZ_CP137113
• Coordinates: 869316..870332 (-)
• Length: 338 a.a.
• NCBI ID: WP_075218762.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ZGX
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 864316..875332

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4707_RS04670	-	864393..864524 (-)	132	WP_000768904.1	hypothetical protein	-
R4707_RS04675	-	864525..865715 (-)	1191	WP_000167766.1	acetate kinase	-
R4707_RS04680	comYH	865766..866719 (-)	954	WP_000345100.1	class I SAM-dependent methyltransferase	Machinery gene
R4707_RS04685	-	866780..867374 (-)	595	Protein_892	class I SAM-dependent methyltransferase	-
R4707_RS04690	comGG/cglG	867511..867924 (-)	414	WP_000265631.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4707_RS04695	comGF/cglF	867902..868363 (-)	462	WP_050104011.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4707_RS04700	comGE/cglE	868326..868628 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4707_RS04705	comGD/cglD	868591..868995 (-)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4707_RS04710	comGC/cglC	868988..869314 (-)	327	WP_000738632.1	comG operon protein ComGC	Machinery gene
R4707_RS04715	comGB/cglB	869316..870332 (-)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4707_RS04720	comGA/cglA/cilD	870280..871221 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R4707_RS04725	-	871297..871662 (-)	366	WP_000286415.1	DUF1033 family protein	-
R4707_RS04730	-	871813..872871 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4707_RS04735	nagA	873034..874185 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 338 a.a.
• Molecular weight: 38478.51 Da
• Isoelectric Point: 9.6073

>NTDB_id=896106 R4707_RS04715 WP_075218762.1 869316..870332(-) (comGB/cglB) [Streptococcus pneumoniae strain ZGX]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVIQMRAGLSQGKSFSEMMESLGFSSTI
ITQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide

• Length: 1017 bp

>NTDB_id=896106 R4707_RS04715 WP_075218762.1 869316..870332(-) (comGB/cglB) [Streptococcus pneumoniae strain ZGX]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGATCCAGATGCGTGCGGGCTTGTCTCAAGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATTTTCAAGCACCATT
ATCACTCAGTTATCCCTAGCTGAAGTTCATGGAAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCAAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (24-141)

• Type II secretion system (T2SS), protein F (T2SSF) (209-329)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB/cglB	Streptococcus pneumoniae Rx1	98.225	100	0.982
comGB/cglB	Streptococcus pneumoniae D39	98.225	100	0.982
comGB/cglB	Streptococcus pneumoniae R6	98.225	100	0.982
comGB/cglB	Streptococcus pneumoniae TIGR4	98.225	100	0.982
comGB/cglB	Streptococcus mitis SK321	94.97	100	0.95
comGB/cglB	Streptococcus mitis NCTC 12261	94.675	100	0.947
comYB	Streptococcus gordonii str. Challis substr. CH1	71.131	99.408	0.707
comYB	Streptococcus mutans UA140	57.862	94.083	0.544
comYB	Streptococcus mutans UA159	57.862	94.083	0.544
comGB	Lactococcus lactis subsp. cremoris KW2	50.898	98.817	0.503