Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R4707_RS04700 Genome accession   NZ_CP137113
Coordinates   868326..868628 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ZGX     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 863326..873628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS04665 rnpA 864005..864376 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R4707_RS04670 - 864393..864524 (-) 132 WP_000768904.1 hypothetical protein -
  R4707_RS04675 - 864525..865715 (-) 1191 WP_000167766.1 acetate kinase -
  R4707_RS04680 comYH 865766..866719 (-) 954 WP_000345100.1 class I SAM-dependent methyltransferase Machinery gene
  R4707_RS04685 - 866780..867374 (-) 595 Protein_892 class I SAM-dependent methyltransferase -
  R4707_RS04690 comGG/cglG 867511..867924 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4707_RS04695 comGF/cglF 867902..868363 (-) 462 WP_050104011.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4707_RS04700 comGE/cglE 868326..868628 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4707_RS04705 comGD/cglD 868591..868995 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4707_RS04710 comGC/cglC 868988..869314 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  R4707_RS04715 comGB/cglB 869316..870332 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4707_RS04720 comGA/cglA/cilD 870280..871221 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R4707_RS04725 - 871297..871662 (-) 366 WP_000286415.1 DUF1033 family protein -
  R4707_RS04730 - 871813..872871 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=896103 R4707_RS04700 WP_000413382.1 868326..868628(-) (comGE/cglE) [Streptococcus pneumoniae strain ZGX]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=896103 R4707_RS04700 WP_000413382.1 868326..868628(-) (comGE/cglE) [Streptococcus pneumoniae strain ZGX]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4