Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Regulator
Locus tag   R4700_RS05560 Genome accession   NZ_CP137112
Coordinates   1080788..1080928 (-) Length   46 a.a.
NCBI ID   WP_000799697.1    Uniprot ID   Q9X9B5
Organism   Streptococcus pneumoniae strain 02H2025     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1075788..1085928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4700_RS05545 - 1077044..1078441 (+) 1398 WP_050279859.1 ISNCY-like element IS1202 family transposase -
  R4700_RS05550 comE 1078701..1079453 (-) 753 WP_000866075.1 competence system response regulator transcription factor ComE Regulator
  R4700_RS05555 comD/comD1 1079450..1080775 (-) 1326 WP_025169508.1 competence system sensor histidine kinase ComD Regulator
  R4700_RS05560 comC 1080788..1080928 (-) 141 WP_000799697.1 competence-stimulating peptide ComC Regulator
  R4700_RS05570 rlmH 1081210..1081689 (-) 480 WP_000695929.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  R4700_RS05575 htrA 1081872..1083053 (+) 1182 WP_000681598.1 S1C family serine protease Regulator
  R4700_RS05580 spo0J 1083111..1083869 (+) 759 WP_000410381.1 ParB/RepB/Spo0J family partition protein Regulator
  R4700_RS05585 dnaA 1084082..1085443 (+) 1362 WP_000660615.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 46 a.a.        Molecular weight: 5673.62 Da        Isoelectric Point: 11.0565

>NTDB_id=896041 R4700_RS05560 WP_000799697.1 1080788..1080928(-) (comC) [Streptococcus pneumoniae strain 02H2025]
MKNTVKLEQFVALKEKDLQNIQGGEMRKMNEKSFNIFNFFNFFRRR

Nucleotide


Download         Length: 141 bp        

>NTDB_id=896041 R4700_RS05560 WP_000799697.1 1080788..1080928(-) (comC) [Streptococcus pneumoniae strain 02H2025]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCTTTGAAGGAAAAAGACTTGCAAAATATTCAAGGTGGGGAGATGAG
GAAAATGAATGAAAAGTCCTTTAATATCTTTAATTTCTTTAATTTCTTTAGAAGAAGATAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9X9B5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus mitis NCTC 12261

67.391

100

0.674
  comC/comC2 Streptococcus pneumoniae A66

92.593

58.696

0.543
  comC/comC2 Streptococcus pneumoniae TIGR4

92.593

58.696

0.543
  comC/comC1 Streptococcus pneumoniae R6

92.593

58.696

0.543
  comC/comC1 Streptococcus pneumoniae G54

92.593

58.696

0.543
  comC/comC1 Streptococcus pneumoniae D39

92.593

58.696

0.543
  comC/comC1 Streptococcus pneumoniae Rx1

92.593

58.696

0.543
  comC Streptococcus mitis SK321

92.593

58.696

0.543