NTDB

Overview

Name	comGF/cglF	Type	Machinery gene
Locus tag	R4702_RS06490	Genome accession	NZ_CP137106
Coordinates	1280421..1280882 (+)	Length	153 a.a.
NCBI ID	WP_000250531.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain 16P4028
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1275421..1285882

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4702_RS06455	-	1275913..1276971 (+)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4702_RS06460	-	1277122..1277487 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4702_RS06465	comGA/cglA/cilD	1277563..1278504 (+)	942	WP_024478452.1	competence type IV pilus ATPase ComGA	Machinery gene
R4702_RS06470	comGB/cglB	1278452..1279468 (+)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4702_RS06475	comGC/cglC	1279470..1279796 (+)	327	WP_000738632.1	comG operon protein ComGC	Machinery gene
R4702_RS06480	comGD/cglD	1279789..1280193 (+)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4702_RS06485	comGE/cglE	1280156..1280458 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4702_RS06490	comGF/cglF	1280421..1280882 (+)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4702_RS06495	comGG/cglG	1280860..1281273 (+)	414	WP_000265631.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4702_RS06500	-	1281410..1282004 (+)	595	Protein_1274	class I SAM-dependent methyltransferase	-
R4702_RS06505	comYH	1282065..1283018 (+)	954	WP_000345100.1	class I SAM-dependent methyltransferase	Machinery gene
R4702_RS06510	-	1283069..1284259 (+)	1191	WP_000167766.1	acetate kinase	-
R4702_RS06515	-	1284260..1284391 (+)	132	WP_000768904.1	hypothetical protein	-
R4702_RS06520	rnpA	1284408..1284779 (+)	372	WP_317809495.1	ribonuclease P protein component	-
R4702_RS06525	-	1284754..1285578 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

Download Length: 153 a.a. Molecular weight: 17849.37 Da Isoelectric Point: 6.4832

                                >NTDB_id=895568 R4702_RS06490 WP_000250531.1 1280421..1280882(+) (comGF/cglF) [Streptococcus pneumoniae strain 16P4028]

MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN

RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

Download Length: 462 bp

                                >NTDB_id=895568 R4702_RS06490 WP_000250531.1 1280421..1280882(+) (comGF/cglF) [Streptococcus pneumoniae strain 16P4028]

ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT

TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG

AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT

CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG

TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT

TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(45-141)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915

Detailed information NTG0895568