Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   R4702_RS06475 Genome accession   NZ_CP137106
Coordinates   1279470..1279796 (+) Length   108 a.a.
NCBI ID   WP_000738632.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P4028     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1274470..1284796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS06450 nagA 1274599..1275750 (+) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  R4702_RS06455 - 1275913..1276971 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  R4702_RS06460 - 1277122..1277487 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4702_RS06465 comGA/cglA/cilD 1277563..1278504 (+) 942 WP_024478452.1 competence type IV pilus ATPase ComGA Machinery gene
  R4702_RS06470 comGB/cglB 1278452..1279468 (+) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4702_RS06475 comGC/cglC 1279470..1279796 (+) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  R4702_RS06480 comGD/cglD 1279789..1280193 (+) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4702_RS06485 comGE/cglE 1280156..1280458 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4702_RS06490 comGF/cglF 1280421..1280882 (+) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4702_RS06495 comGG/cglG 1280860..1281273 (+) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4702_RS06500 - 1281410..1282004 (+) 595 Protein_1274 class I SAM-dependent methyltransferase -
  R4702_RS06505 comYH 1282065..1283018 (+) 954 WP_000345100.1 class I SAM-dependent methyltransferase Machinery gene
  R4702_RS06510 - 1283069..1284259 (+) 1191 WP_000167766.1 acetate kinase -
  R4702_RS06515 - 1284260..1284391 (+) 132 WP_000768904.1 hypothetical protein -
  R4702_RS06520 rnpA 1284408..1284779 (+) 372 WP_317809495.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12180.34 Da        Isoelectric Point: 10.0305

>NTDB_id=895565 R4702_RS06475 WP_000738632.1 1279470..1279796(+) (comGC/cglC) [Streptococcus pneumoniae strain 16P4028]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQVKAYKEYNDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=895565 R4702_RS06475 WP_000738632.1 1279470..1279796(+) (comGC/cglC) [Streptococcus pneumoniae strain 16P4028]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGTTAAAGCTTATAAAGAATACAATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae Rx1

95.37

100

0.954

  comGC/cglC Streptococcus pneumoniae D39

95.37

100

0.954

  comGC/cglC Streptococcus pneumoniae R6

95.37

100

0.954

  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926

  comGC/cglC Streptococcus mitis NCTC 12261

91.919

91.667

0.843

  comYC Streptococcus gordonii str. Challis substr. CH1

66.99

95.37

0.639

  comYC Streptococcus mutans UA159

61.765

94.444

0.583

  comYC Streptococcus mutans UA140

61.765

94.444

0.583

  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528

  comYC Streptococcus suis isolate S10

66.667

75

0.5

  comGC Staphylococcus aureus MW2

48.837

79.63

0.389

  comGC Staphylococcus aureus N315

48.837

79.63

0.389

  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361