Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AAG092_RS00055 Genome accession   NZ_CP154874
Coordinates   8583..9251 (+) Length   222 a.a.
NCBI ID   WP_061904563.1    Uniprot ID   -
Organism   Pseudomonas alcaligenes strain Med1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3583..14251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAG092_RS00030 (AAG092_00030) queD 5922..6278 (-) 357 WP_021700277.1 6-carboxytetrahydropterin synthase QueD -
  AAG092_RS00035 (AAG092_00035) - 6332..6688 (-) 357 WP_373388008.1 DUF5329 family protein -
  AAG092_RS00040 (AAG092_00040) - 6710..7789 (-) 1080 WP_373388009.1 patatin-like phospholipase family protein -
  AAG092_RS00045 (AAG092_00045) - 7961..8269 (+) 309 WP_021700274.1 PepSY domain-containing protein -
  AAG092_RS00050 (AAG092_00050) - 8269..8583 (+) 315 WP_373388010.1 PepSY domain-containing protein -
  AAG092_RS00055 (AAG092_00055) ciaR 8583..9251 (+) 669 WP_061904563.1 response regulator transcription factor Regulator
  AAG092_RS00060 (AAG092_00060) - 9248..10564 (+) 1317 WP_373388011.1 sensor histidine kinase -
  AAG092_RS00065 (AAG092_00065) - 10565..11161 (-) 597 WP_373388012.1 NADPH-dependent FMN reductase -
  AAG092_RS00070 - 11290..12045 (-) 756 WP_373389539.1 methyl-accepting chemotaxis protein -
  AAG092_RS00075 - 12148..13431 (-) 1284 Protein_9 HAMP domain-containing protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24719.07 Da        Isoelectric Point: 5.3708

>NTDB_id=893838 AAG092_RS00055 WP_061904563.1 8583..9251(+) (ciaR) [Pseudomonas alcaligenes strain Med1]
MRLLLVEDHVPLADELLVSLKGQGYAVDWLADGRDAAYQGATEPYDLIILDLGLPGKPGLEVLREWRAGGLSTPVLILTA
RGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQPQLEAAGLQLDESRQCVTRGSEQIELTSAEFRLLR
YFMLHPGQILSKSQLADHLYDGESERDSNVLEVHVNRLRGKLGREVIETRRGQGYRYAGVDT

Nucleotide


Download         Length: 669 bp        

>NTDB_id=893838 AAG092_RS00055 WP_061904563.1 8583..9251(+) (ciaR) [Pseudomonas alcaligenes strain Med1]
ATGCGCCTGTTGCTGGTGGAAGACCATGTGCCCCTGGCCGATGAACTGCTGGTCAGCCTCAAAGGGCAGGGCTATGCGGT
GGACTGGCTGGCCGATGGCCGTGATGCCGCCTATCAGGGGGCAACCGAGCCTTATGACCTGATCATTCTCGACCTCGGCT
TGCCGGGCAAGCCGGGGCTCGAGGTGCTGCGTGAGTGGCGCGCCGGCGGCCTGAGCACGCCCGTGCTGATTCTGACGGCG
CGCGGTTCCTGGGCCGAGCGCATCGATGGTCTCAAGGCCGGCGCCGACGACTACCTGACCAAACCCTTCCATCCCGAAGA
GCTGGCCCTGCGTATCCAGGCGCTGTTGCGCCGCGCCCACGGCCTGGCCAACCAGCCGCAGCTGGAGGCTGCCGGGCTGC
AGCTGGACGAAAGCCGCCAGTGCGTGACGCGTGGCAGTGAGCAGATCGAGCTGACGTCCGCCGAGTTCCGCCTGCTGCGC
TACTTCATGCTGCATCCCGGGCAGATCCTGTCCAAGAGCCAGCTGGCCGACCATCTCTATGATGGCGAGAGCGAGCGCGA
CTCCAATGTCCTGGAGGTGCATGTCAATCGCCTGCGCGGCAAGCTCGGGCGCGAGGTGATAGAGACCCGGCGTGGCCAGG
GTTACCGTTACGCCGGGGTCGACACTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

40.183

98.649

0.396
  ciaR Streptococcus pneumoniae Rx1

40.183

98.649

0.396
  ciaR Streptococcus pneumoniae D39

40.183

98.649

0.396
  ciaR Streptococcus pneumoniae R6

40.183

98.649

0.396
  ciaR Streptococcus mutans UA159

39.726

98.649

0.392
  vicR Streptococcus mutans UA159

35.745

100

0.378
  covR Streptococcus salivarius strain HSISS4

36.486

100

0.365
  micA Streptococcus pneumoniae Cp1015

35.242

100

0.36