Detailed information NTG0893654

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: R3H60_RS04515
• Genome accession: NZ_CP136950
• Coordinates: 897578..898414 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Spyo06
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 892578..903414

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R3H60_RS04485 (R3H60_04475)	-	893132..893500 (+)	369	WP_010922310.1	hypothetical protein	-
R3H60_RS04490 (R3H60_04480)	-	893550..894461 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
R3H60_RS04495 (R3H60_04485)	trhA	894578..895228 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
R3H60_RS04500 (R3H60_04490)	-	895225..895665 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
R3H60_RS04505 (R3H60_04495)	ylqF	895884..896732 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
R3H60_RS04510 (R3H60_04500)	-	896722..897513 (+)	792	WP_011285534.1	ribonuclease HII	-
R3H60_RS04515 (R3H60_04505)	dprA	897578..898414 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
R3H60_RS04520 (R3H60_04510)	topA	898521..900650 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
R3H60_RS04525 (R3H60_04515)	-	900725..901607 (-)	883	Protein_845	LysR family transcriptional regulator	-
R3H60_RS04530 (R3H60_04520)	-	901620..902165 (+)	546	Protein_846	PTS sugar transporter subunit IIC	-
R3H60_RS04535 (R3H60_04525)	-	902180..903172 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=893654 R3H60_RS04515 WP_010922314.1 897578..898414(+) (dprA) [Streptococcus pyogenes strain Spyo06]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=893654 R3H60_RS04515 WP_010922314.1 897578..898414(+) (dprA) [Streptococcus pyogenes strain Spyo06]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367