Detailed information NTG0893609

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: R3H37_RS04745
• Genome accession: NZ_CP136948
• Coordinates: 943676..944512 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Spyo01
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 938676..949512

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R3H37_RS04725 (R3H37_04725)	-	938895..939887 (-)	993	WP_330554578.1	D-lactate dehydrogenase	-
R3H37_RS04730 (R3H37_04730)	-	939902..940468 (-)	567	Protein_873	PTS sugar transporter subunit IIC	-
R3H37_RS04735 (R3H37_04735)	-	940508..941365 (+)	858	Protein_874	LysR family transcriptional regulator	-
R3H37_RS04740 (R3H37_04740)	topA	941440..943569 (-)	2130	WP_030125930.1	type I DNA topoisomerase	-
R3H37_RS04745 (R3H37_04745)	dprA	943676..944512 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
R3H37_RS04750 (R3H37_04750)	-	944577..945368 (-)	792	WP_030125931.1	ribonuclease HII	-
R3H37_RS04755 (R3H37_04755)	ylqF	945358..946206 (-)	849	WP_030125932.1	ribosome biogenesis GTPase YlqF	-
R3H37_RS04760 (R3H37_04760)	-	946425..946865 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
R3H37_RS04765 (R3H37_04765)	trhA	946862..947512 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
R3H37_RS04770 (R3H37_04770)	-	947629..948540 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
R3H37_RS04775 (R3H37_04775)	-	948590..948964 (-)	375	WP_023611058.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=893609 R3H37_RS04745 WP_002989770.1 943676..944512(-) (dprA) [Streptococcus pyogenes strain Spyo01]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=893609 R3H37_RS04745 WP_002989770.1 943676..944512(-) (dprA) [Streptococcus pyogenes strain Spyo01]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367