Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   RJD36_RS02295 Genome accession   NZ_CP136943
Coordinates   422118..423998 (+) Length   626 a.a.
NCBI ID   WP_270620180.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain WUSP082     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 417118..428998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJD36_RS02280 (RJD36_02280) fmt 419096..420031 (+) 936 WP_069789206.1 methionyl-tRNA formyltransferase -
  RJD36_RS02285 (RJD36_02285) rsmB 420021..421343 (+) 1323 WP_317751411.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  RJD36_RS02290 (RJD36_02290) - 421381..422118 (+) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RJD36_RS02295 (RJD36_02295) pknB 422118..423998 (+) 1881 WP_270620180.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RJD36_RS02300 (RJD36_02300) liaF 424093..424788 (+) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  RJD36_RS02305 (RJD36_02305) - 424785..425810 (+) 1026 WP_117479650.1 sensor histidine kinase -
  RJD36_RS02310 (RJD36_02310) - 425794..426438 (+) 645 WP_013851527.1 response regulator transcription factor -
  RJD36_RS02315 (RJD36_02315) - 426556..427956 (+) 1401 WP_069789204.1 Cof-type HAD-IIB family hydrolase -
  RJD36_RS02320 (RJD36_02320) - 427956..428312 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 67892.18 Da        Isoelectric Point: 5.0714

>NTDB_id=893534 RJD36_RS02295 WP_270620180.1 422118..423998(+) (pknB) [Streptococcus pasteurianus strain WUSP082]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGLDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KVATENQATKAKTKKKKSRRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHK
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGSSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGETFKVSGDDKITFKVATESTVTMPNLTGYTYSEAIAALTALGVSSSHITVYQADPNSSTGYVQVSSPSST
ATITAQTPYYGETLSGNVILYLAADEEESSQAPSSSSSEPSESKESSSSSSSTDDSSSSTESSNEQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=893534 RJD36_RS02295 WP_270620180.1 422118..423998(+) (pknB) [Streptococcus pasteurianus strain WUSP082]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTGGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATCGTCTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGATTGGACTTGAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTATCTGCGATGACTTTGGCGCATCAACAAGGGATTGTTC
ACCGTGATTTAAAACCACAAAATATCTTATTAACCAAAGATGGAACTGTTAAAGTTACTGACTTTGGTATCGCCGTAGCC
TTTGCCGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCTATCATTGATGAGAATAAGAATGTTCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTCTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGTAGCAACAGAAAACCAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACGTCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACTTACTTGACGTTGACCTCACCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACCGTTCATAAA
GTATCAAGTGATACCGTTGAGAGTGGTTACGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTCATCAGGATTCAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATAATTACGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGACTATGACGAAGGT
GTTATCATCAGTCAAACGCCTAGTGAAGGTGAAACCTTTAAGGTAAGTGGTGATGATAAGATTACCTTTAAAGTAGCCAC
AGAAAGTACAGTGACAATGCCGAATTTGACAGGCTATACTTATTCAGAAGCTATTGCTGCCTTAACAGCTCTAGGCGTGT
CAAGTTCACATATTACGGTTTATCAAGCCGACCCAAATTCTTCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTATCACTGCTCAAACACCTTACTATGGTGAAACGTTAAGTGGTAACGTGATACTTTACCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCGCCATCGTCATCAAGTTCAGAACCCTCTGAATCAAAAGAATCAAGTTCATCAAGTAGCAGTACAG
ATGATAGTAGCTCATCAACAGAATCAAGTAATGAACAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-247)

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(511-575)

PASTA domain (PASTA)

(440-506)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

68.313

93.77

0.641
  stkP/pknB Streptococcus salivarius strain HSISS4

64.478

94.888

0.612
  stkP Streptococcus pneumoniae TIGR4

54.623

93.291

0.51
  stkP Streptococcus pneumoniae D39

54.452

93.291

0.508
  stkP Streptococcus pneumoniae R6

54.452

93.291

0.508
  stkP Streptococcus pneumoniae Rx1

54.281

93.291

0.506