Detailed information NTG0892736

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: RYQ61_RS06940
• Genome accession: NZ_CP136799
• Coordinates: 1338902..1341052 (+)
• Length: 716 a.a.
• NCBI ID: WP_102567749.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain XH2169
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1333902..1346052

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RYQ61_RS06910 (RYQ61_06910)	pyrH	1333933..1334673 (+)	741	WP_003069937.1	UMP kinase	-
RYQ61_RS06915 (RYQ61_06915)	frr	1334677..1335234 (+)	558	WP_102567753.1	ribosome recycling factor	-
RYQ61_RS06920 (RYQ61_06920)	cvfB	1335347..1336201 (+)	855	WP_102567752.1	RNA-binding virulence regulatory protein CvfB	-
RYQ61_RS06925 (RYQ61_06925)	holA	1336261..1337298 (+)	1038	WP_102567751.1	DNA polymerase III subunit delta	-
RYQ61_RS06930 (RYQ61_06930)	-	1337369..1337974 (+)	606	WP_003073371.1	superoxide dismutase	-
RYQ61_RS06935 (RYQ61_06935)	-	1338047..1338421 (-)	375	WP_003073369.1	hypothetical protein	-
RYQ61_RS06940 (RYQ61_06940)	comA/nlmT	1338902..1341052 (+)	2151	WP_102567749.1	peptide cleavage/export ABC transporter	Regulator
RYQ61_RS06945 (RYQ61_06945)	-	1341063..1342424 (+)	1362	WP_048786129.1	bacteriocin secretion accessory protein	-
RYQ61_RS06950 (RYQ61_06950)	-	1342521..1342673 (+)	153	WP_102567748.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
RYQ61_RS06955 (RYQ61_06955)	-	1342754..1344070 (-)	1317	WP_102567747.1	sensor histidine kinase	-
RYQ61_RS06960 (RYQ61_06960)	comE/blpR	1344072..1344818 (-)	747	WP_037582857.1	response regulator transcription factor	Regulator
RYQ61_RS06965 (RYQ61_06965)	-	1344987..1345700 (-)	714	WP_102567746.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80458.04 Da
• Isoelectric Point: 9.3439

>NTDB_id=892736 RYQ61_RS06940 WP_102567749.1 1338902..1341052(+) (comA/nlmT) [Streptococcus intermedius strain XH2169]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKGKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMRSTLGIVSIGLIITYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSILIIVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEEARYQKIDSEFVNYLDKSFTLSKYSIFQTTLKQGFQLI
LNVLILWLGAHLVISEKISIGQLITFTALLSYFTNSLESIINLQTKLQSAKVANKRLNEVYSVESEFKTKQTLIEKGFLT
GDITFHNVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGMNQIFSQKEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHAELMERQGFYHHLFNK

Nucleotide

• Length: 2151 bp

>NTDB_id=892736 RYQ61_RS06940 WP_102567749.1 1338902..1341052(+) (comA/nlmT) [Streptococcus intermedius strain XH2169]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAACAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGGTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACCAAGATCTCAAAAGAAACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTTTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
CCTACAAGGAATTTTAGATGAATACATTCCAAATCAAATGAGATCAACTCTTGGAATAGTGTCTATTGGTCTGATTATTA
CTTATATTTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTGTACTTAGTCAGCGGCTGACCATCGATGTG
ATTTTATCATATATTCGACACATTTTTGAATTACCAATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTCTATTTTGATAA
TAGTAGGAGGGGTATTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGCAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAGCTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCTATTTTTCAAACAACTCTTAAACAAGGCTTTCAATTAATT
TTAAATGTGCTTATTTTATGGCTCGGTGCGCATTTAGTTATATCTGAGAAAATCTCAATTGGGCAGCTCATCACATTTAC
GGCTCTACTTTCTTATTTTACAAATTCTCTTGAAAGTATTATTAATCTGCAAACTAAGCTGCAGTCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATTCAGTAGAGTCTGAATTTAAAACTAAGCAAACACTTATAGAGAAAGGTTTCTTGACT
GGTGATATTACGTTCCATAATGTCTCCTATAAATACGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGACCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCTATCTTAGAAAATCTTACATTAGGGATGAATCAAATATTTTCTCA
AAAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAACGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGACGAAGCGACGAGTGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGTTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGAACAAATCAGGTTATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATCCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (499-648)

• Peptidase C39 family (Peptidase_C39) (6-141)

• ABC transporter transmembrane region (ABC_membrane) (168-437)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.073	99.022	0.714
comA	Streptococcus mitis NCTC 12261	66.62	99.581	0.663
comA	Streptococcus mitis SK321	66.48	99.581	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	66.059	99.581	0.658
comA	Streptococcus pneumoniae D39	65.919	99.581	0.656
comA	Streptococcus pneumoniae R6	65.919	99.581	0.656
comA	Streptococcus pneumoniae Rx1	65.919	99.581	0.656
comA	Streptococcus pneumoniae TIGR4	65.498	99.581	0.652