Detailed information NTG0892737

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: RYQ61_RS06960
• Genome accession: NZ_CP136799
• Coordinates: 1344072..1344818 (-)
• Length: 248 a.a.
• NCBI ID: WP_037582857.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain XH2169
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1339072..1349818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RYQ61_RS06945 (RYQ61_06945)	-	1341063..1342424 (+)	1362	WP_048786129.1	bacteriocin secretion accessory protein	-
RYQ61_RS06950 (RYQ61_06950)	-	1342521..1342673 (+)	153	WP_102567748.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
RYQ61_RS06955 (RYQ61_06955)	-	1342754..1344070 (-)	1317	WP_102567747.1	sensor histidine kinase	-
RYQ61_RS06960 (RYQ61_06960)	comE/blpR	1344072..1344818 (-)	747	WP_037582857.1	response regulator transcription factor	Regulator
RYQ61_RS06965 (RYQ61_06965)	-	1344987..1345700 (-)	714	WP_102567746.1	CPBP family intramembrane glutamic endopeptidase	-
RYQ61_RS06970 (RYQ61_06970)	-	1346030..1346155 (+)	126	WP_003037205.1	hypothetical protein	-
RYQ61_RS06975 (RYQ61_06975)	-	1346243..1346563 (+)	321	WP_003037422.1	hypothetical protein	-
RYQ61_RS06980 (RYQ61_06980)	-	1346571..1346792 (+)	222	WP_003025422.1	Blp family class II bacteriocin	-
RYQ61_RS06985 (RYQ61_06985)	-	1347107..1347358 (+)	252	WP_020998893.1	hypothetical protein	-
RYQ61_RS06990 (RYQ61_06990)	-	1347569..1347784 (+)	216	WP_041823339.1	bacteriocin class II family protein	-
RYQ61_RS06995 (RYQ61_06995)	-	1348013..1348306 (+)	294	WP_003073345.1	bacteriocin immunity protein	-
RYQ61_RS07000 (RYQ61_07000)	-	1348400..1348627 (+)	228	WP_041823245.1	hypothetical protein	-
RYQ61_RS07005 (RYQ61_07005)	-	1348663..1348983 (+)	321	WP_020998890.1	hypothetical protein	-
RYQ61_RS07010 (RYQ61_07010)	-	1349213..1349431 (+)	219	WP_020998889.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 248 a.a.
• Molecular weight: 28725.13 Da
• Isoelectric Point: 7.6681

>NTDB_id=892737 RYQ61_RS06960 WP_037582857.1 1344072..1344818(-) (comE/blpR) [Streptococcus intermedius strain XH2169]
MNIFILEDDLTQQYYMETIVEEIIEKHRLQYHHFEVFGKPKQLLEAISEKGSHQVFFLDIEIKTEEKKGLDVAKKIREID
PYAIIVFVTSHSELMPAAFKLQVGALDYLDKSLSKEALKKRIETALLHTENLTGKGLADDSLLFETPHTQIQVPFKDILY
IETSSRPHRLVLYTHRGRTEFTANLSDMLKKEKRFYQCHRSFVVNPANVHQVDKVNHILHFQNGATCLVSRSKIKGLTEA
IAALHRRE

Nucleotide

• Length: 747 bp

>NTDB_id=892737 RYQ61_RS06960 WP_037582857.1 1344072..1344818(-) (comE/blpR) [Streptococcus intermedius strain XH2169]
ATGAATATTTTTATTTTAGAAGATGATCTTACTCAACAATATTATATGGAGACTATTGTTGAAGAAATTATCGAAAAACA
TCGTCTTCAATATCACCATTTTGAAGTTTTTGGAAAACCTAAACAATTACTAGAAGCCATATCTGAGAAAGGAAGCCATC
AGGTTTTCTTTTTGGATATTGAAATCAAAACTGAAGAAAAAAAGGGCTTAGACGTCGCCAAAAAGATACGCGAGATAGAT
CCTTATGCCATTATTGTCTTTGTAACCAGTCACTCTGAATTGATGCCGGCAGCGTTTAAACTGCAAGTCGGCGCCCTTGA
CTATCTTGACAAATCGTTATCAAAAGAAGCTTTGAAAAAACGGATCGAAACTGCGCTGCTACATACTGAAAACCTAACAG
GCAAAGGCCTGGCAGACGATTCTCTTCTCTTTGAAACACCTCATACACAAATACAAGTGCCGTTTAAAGATATTCTTTAC
ATTGAAACTTCCTCTCGTCCTCACCGTTTAGTACTTTACACACATAGAGGGCGTACGGAATTTACTGCCAATCTTTCAGA
TATGTTAAAAAAAGAAAAACGGTTCTACCAATGTCATCGTTCCTTTGTTGTTAACCCAGCTAATGTCCATCAAGTGGATA
AAGTAAATCATATCCTTCACTTCCAGAATGGTGCTACTTGTCTTGTTTCTAGATCAAAAATAAAAGGGTTAACAGAAGCT
ATTGCAGCCCTGCACCGGAGGGAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-123)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	49.798	99.597	0.496
comE/comE1	Streptococcus equinus JB1	45.992	95.565	0.44