Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   F6I35_RS04000 Genome accession   NZ_CP136160
Coordinates   760715..761416 (+) Length   233 a.a.
NCBI ID   WP_003025150.1    Uniprot ID   A0A2I1UXK8
Organism   Streptococcus anginosus strain UMB8616     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 755715..766416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS03980 (F6I35_0003980) ccpA 756656..757660 (+) 1005 WP_024051861.1 catabolite control protein A Regulator
  F6I35_RS03985 (F6I35_0003985) - 757753..758751 (+) 999 WP_024051860.1 glycosyltransferase family 4 protein -
  F6I35_RS03990 (F6I35_0003990) - 758753..760066 (+) 1314 WP_101750292.1 glycosyltransferase family 4 protein -
  F6I35_RS03995 (F6I35_0003995) - 760093..760434 (+) 342 WP_070584168.1 hypothetical protein -
  F6I35_RS04000 (F6I35_0004000) micA 760715..761416 (+) 702 WP_003025150.1 response regulator YycF Regulator
  F6I35_RS04005 (F6I35_0004005) micB 761409..762761 (+) 1353 WP_150866955.1 cell wall metabolism sensor histidine kinase VicK Regulator
  F6I35_RS04010 (F6I35_0004010) vicX 762763..763566 (+) 804 WP_024051857.1 MBL fold metallo-hydrolase Regulator
  F6I35_RS04015 (F6I35_0004015) - 763600..763914 (+) 315 Protein_753 YbaN family protein -
  F6I35_RS04020 (F6I35_0004020) rnc 764295..764993 (+) 699 WP_003025140.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26887.86 Da        Isoelectric Point: 4.6824

>NTDB_id=888962 F6I35_RS04000 WP_003025150.1 760715..761416(+) (micA) [Streptococcus anginosus strain UMB8616]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=888962 F6I35_RS04000 WP_003025150.1 760715..761416(+) (micA) [Streptococcus anginosus strain UMB8616]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAGCCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTTGACGGTCGCGAAGCGTTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAAATGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGCGAATTTGACAAAGTTATTGGTCTTGAAATCGGTGCGGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTCAAAGCCATTTTGCGGCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTCCACCATTTGGCAACGCATATCGGACAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UXK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361