Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   F6I35_RS04005 Genome accession   NZ_CP136160
Coordinates   761409..762761 (+) Length   450 a.a.
NCBI ID   WP_150866955.1    Uniprot ID   -
Organism   Streptococcus anginosus strain UMB8616     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 756409..767761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS03980 (F6I35_0003980) ccpA 756656..757660 (+) 1005 WP_024051861.1 catabolite control protein A Regulator
  F6I35_RS03985 (F6I35_0003985) - 757753..758751 (+) 999 WP_024051860.1 glycosyltransferase family 4 protein -
  F6I35_RS03990 (F6I35_0003990) - 758753..760066 (+) 1314 WP_101750292.1 glycosyltransferase family 4 protein -
  F6I35_RS03995 (F6I35_0003995) - 760093..760434 (+) 342 WP_070584168.1 hypothetical protein -
  F6I35_RS04000 (F6I35_0004000) micA 760715..761416 (+) 702 WP_003025150.1 response regulator YycF Regulator
  F6I35_RS04005 (F6I35_0004005) micB 761409..762761 (+) 1353 WP_150866955.1 cell wall metabolism sensor histidine kinase VicK Regulator
  F6I35_RS04010 (F6I35_0004010) vicX 762763..763566 (+) 804 WP_024051857.1 MBL fold metallo-hydrolase Regulator
  F6I35_RS04015 (F6I35_0004015) - 763600..763914 (+) 315 Protein_753 YbaN family protein -
  F6I35_RS04020 (F6I35_0004020) rnc 764295..764993 (+) 699 WP_003025140.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51342.60 Da        Isoelectric Point: 4.6876

>NTDB_id=888963 F6I35_RS04005 WP_150866955.1 761409..762761(+) (micB) [Streptococcus anginosus strain UMB8616]
MIDNIRQFIVSKDFVFVLLILGFILVITLLSLENRRDNIRIRQLNQKVKDLIAGNYSEILDVQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDIEDEYDLRDLITKVPE
LTIDSQDENGEILSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTDTQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=888963 F6I35_RS04005 WP_150866955.1 761409..762761(+) (micB) [Streptococcus anginosus strain UMB8616]
ATGATTGATAATATTAGACAATTTATTGTATCAAAAGACTTTGTATTTGTTTTACTTATTTTAGGGTTCATCTTGGTGAT
TACCTTGCTTTCCTTGGAAAATAGGCGAGACAATATTCGTATTCGCCAATTGAATCAAAAAGTAAAAGATTTAATTGCAG
GCAATTACTCAGAAATTTTAGATGTACAAGGTGGTCCAGAAATTACGGATATTACCAATAGTATCAATGATTTATCTGAG
GTAATCCGTCTAACGCATGAAAATTTAGAGCAAGAAACTAAGCGCCTGTCGAGTATTTTATCCTATATGACGGACGGTGT
TCTTGCGACCAATCGTCGTGGGCAGATTATCATGATCAATGATATGGCAACCAAGCAGTTGGGGGTCAAAGAGTCTGAAG
CACGAAAGATGAATATCTTAAAACTGTTGGATATCGAAGACGAATATGACTTACGAGACTTGATTACGAAAGTTCCAGAG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGATTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGGCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCAGTGCTACACGATACAACGGAGCAGGAAAAAGAAGAGCGTGAGCGGAGACTGTTTGTTT
CGAATGTCAGTCACGAATTACGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCACTAGATGAAGGTGCCTTATCA
GAACCAGTCGCACCGGATTTCATCAAGGTTTCATTAGACGAGACCAATCGGATGATGCGCATGGTTTCGGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACAGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGCCAGAATGATGATAAAAAGTATGAAATTATACGAGATTATCCGATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
CAAGATTACGGTCAGTATGAAAACGACGGATACCCAAATGATTTTGTCGATTTCAGATGAAGGCTTAGGAATTCCTAAAA
AAGATTTACCGAAAATTTTTGATAGATTTTATCGTGTAGATAAAGCGAGAAGTCGTGCACAAGGTGGGTCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAGCATAACGGCTTTATCTGGGCAAAGAGCGAGTACGGCAAAGGTTCAACCTT
TACTATTGTCCTGCCTTATGATAAGGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.093

97.556

0.791
  vicK Streptococcus mutans UA159

71.638

90.889

0.651