Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   RSK81_RS04960 Genome accession   NZ_CP135591
Coordinates   1015396..1016070 (+) Length   224 a.a.
NCBI ID   WP_002917388.1    Uniprot ID   -
Organism   Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1010396..1021070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RSK81_RS04940 (RSK81_04940) - 1013145..1013429 (+) 285 WP_002917391.1 helix-turn-helix domain-containing protein -
  RSK81_RS04945 (RSK81_04945) - 1013485..1013811 (+) 327 WP_002900559.1 DMT family transporter -
  RSK81_RS04950 (RSK81_04950) - 1013815..1014630 (+) 816 WP_315687619.1 SDR family NAD(P)-dependent oxidoreductase -
  RSK81_RS04955 (RSK81_04955) - 1014810..1015291 (+) 482 Protein_957 hypothetical protein -
  RSK81_RS04960 (RSK81_04960) ciaR 1015396..1016070 (+) 675 WP_002917388.1 response regulator transcription factor Regulator
  RSK81_RS04965 (RSK81_04965) ciaH 1016060..1017451 (+) 1392 WP_002900556.1 sensor histidine kinase Regulator
  RSK81_RS04970 (RSK81_04970) - 1017467..1018405 (+) 939 WP_049553076.1 ketopantoate reductase family protein -
  RSK81_RS04975 (RSK81_04975) - 1018517..1018903 (+) 387 WP_002895748.1 VOC family protein -
  RSK81_RS04980 (RSK81_04980) - 1018965..1020362 (+) 1398 WP_315687621.1 polysaccharide deacetylase family protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25179.86 Da        Isoelectric Point: 4.4858

>NTDB_id=887032 RSK81_RS04960 WP_002917388.1 1015396..1016070(+) (ciaR) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
MIKILLVEDDLGLSNSVFDFLDDFADVTQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKDLRAKGVTTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLSYGDVTVNLSTNSTTKAGKDVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTVSVVEVYVSKIRKKLKGTAFAKNLHTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=887032 RSK81_RS04960 WP_002917388.1 1015396..1016070(+) (ciaR) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
ATGATTAAAATTCTATTGGTAGAAGATGACCTTGGACTGTCAAACTCAGTTTTTGATTTTTTAGATGATTTTGCAGATGT
AACGCAGGTTTTTGATGGTGAAGAAGGTCTATATGAAGCAGAAAGCGGTGTTTATGACCTCATCTTACTGGATCTCATGC
TGCCTGAAAAGGATGGTTTCCAAGTGCTGAAAGATCTCCGAGCAAAAGGAGTCACAACCCCTGTCCTCATCATGACAGCT
AAGGAAAGCTTGGATGACAAAGGACATGGCTTTGAGCTAGGCGCTGACGACTATCTGACAAAACCTTTCTATTTGGAAGA
ACTGAAAATGCGGATCCAAGCGCTCTTGAAACGCGCTGGTAAATTCAACGAGAATACTCTTTCTTATGGTGATGTAACTG
TCAACCTATCTACAAATTCGACTACGAAGGCGGGTAAAGATGTAGAGTTGCTTGGTAAAGAGTTCGACCTCTTGGTTTAT
TTCCTGCAAAATCAAAATGTAATCTTGCCTAAGACTCAAATTTTTGACCGTCTGTGGGGCTTTGACAGTGATACCACTGT
TTCCGTTGTCGAAGTGTACGTTTCAAAGATTCGTAAAAAACTGAAAGGAACGGCATTTGCGAAAAACCTACATACTCTTC
GTAGTGTCGGCTACATTTTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

88.393

100

0.884
  ciaR Streptococcus pneumoniae D39

88.393

100

0.884
  ciaR Streptococcus pneumoniae R6

88.393

100

0.884
  ciaR Streptococcus pneumoniae TIGR4

88.393

100

0.884
  ciaR Streptococcus mutans UA159

86.996

99.554

0.866
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.648

100

0.402
  vicR Streptococcus mutans UA159

35.622

100

0.371