Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RSK81_RS04965 Genome accession   NZ_CP135591
Coordinates   1016060..1017451 (+) Length   463 a.a.
NCBI ID   WP_002900556.1    Uniprot ID   A0AA96NT01
Organism   Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1011060..1022451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RSK81_RS04940 (RSK81_04940) - 1013145..1013429 (+) 285 WP_002917391.1 helix-turn-helix domain-containing protein -
  RSK81_RS04945 (RSK81_04945) - 1013485..1013811 (+) 327 WP_002900559.1 DMT family transporter -
  RSK81_RS04950 (RSK81_04950) - 1013815..1014630 (+) 816 WP_315687619.1 SDR family NAD(P)-dependent oxidoreductase -
  RSK81_RS04955 (RSK81_04955) - 1014810..1015291 (+) 482 Protein_957 hypothetical protein -
  RSK81_RS04960 (RSK81_04960) ciaR 1015396..1016070 (+) 675 WP_002917388.1 response regulator transcription factor Regulator
  RSK81_RS04965 (RSK81_04965) ciaH 1016060..1017451 (+) 1392 WP_002900556.1 sensor histidine kinase Regulator
  RSK81_RS04970 (RSK81_04970) - 1017467..1018405 (+) 939 WP_049553076.1 ketopantoate reductase family protein -
  RSK81_RS04975 (RSK81_04975) - 1018517..1018903 (+) 387 WP_002895748.1 VOC family protein -
  RSK81_RS04980 (RSK81_04980) - 1018965..1020362 (+) 1398 WP_315687621.1 polysaccharide deacetylase family protein -
  RSK81_RS04985 (RSK81_04985) - 1020458..1021549 (-) 1092 WP_002912245.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 463 a.a.        Molecular weight: 52645.05 Da        Isoelectric Point: 8.4955

>NTDB_id=887033 RSK81_RS04965 WP_002900556.1 1016060..1017451(+) (ciaH) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
MLNKIKKTFYADDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTSVDENLRNLSNDPSSVADLAYRTTGQQSDPSNKVN
TKSPKSSKEPDGDSDEEPKPNNLTTPNVSSNTFALLLDDDYKNISTSKSDGFLDFNSLEFNKSYLNQIKEIVIGNSFGQT
ESYRAYLFDIDPKNEYPDIKYAVVMTSISQLEQTSSKHEQLIAMVMVSFWGISLIASIYLARMSVKPLLESIQKQKAFVE
NASHELRTPLAVLQSRLETLFRKPEATIMQSSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPQYGEVEPEFFDTTFAN
YCIIARENKKAFHSENMIKHPIVTDQIFLKQLMTILFDNAIKYTDDDGVISVMATSTDRYLIFRVADNGPGISDEDKKKI
FDRFYRVDKARTRQKGGFGLGLSLAKQIVDAFKGSIYVKDNKPKGTVFEVKLLLKETKKRSVK

Nucleotide


Download         Length: 1392 bp        

>NTDB_id=887033 RSK81_RS04965 WP_002900556.1 1016060..1017451(+) (ciaH) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
ATGCTGAATAAAATCAAGAAGACCTTTTATGCGGATGATTTCTCTTATTTCATTCGCTATTTTGGGTTGTTTACATTAAT
CTTCTCAGCCATGACCTTGATTATTATTCAGGTTATGCGCTCCAGCCTTTATACGTCAGTTGATGAAAATCTGAGGAATC
TGAGTAATGATCCTAGTTCGGTAGCTGATTTGGCCTATCGGACGACAGGTCAGCAGTCTGATCCGAGCAATAAGGTCAAC
ACTAAAAGTCCTAAAAGCAGTAAAGAGCCAGATGGTGATTCAGATGAAGAGCCTAAGCCTAACAATCTAACTACGCCAAA
TGTCAGCTCTAATACCTTTGCCCTGCTTTTGGATGATGATTATAAAAATATTTCCACCAGCAAGAGCGATGGTTTTCTGG
ACTTTAATTCATTAGAGTTTAACAAGTCCTATCTGAATCAAATCAAGGAGATTGTGATTGGCAACAGCTTTGGTCAGACA
GAAAGCTATCGGGCTTATCTCTTTGATATTGATCCTAAAAATGAGTACCCTGATATCAAGTACGCTGTGGTCATGACTAG
TATCAGCCAGCTGGAGCAGACCAGCAGCAAGCATGAGCAACTGATTGCCATGGTTATGGTCAGCTTTTGGGGAATTTCCC
TGATTGCCAGTATTTATCTGGCTCGGATGAGTGTCAAGCCTCTGCTGGAAAGTATCCAGAAGCAGAAGGCTTTCGTGGAA
AATGCCAGTCACGAGCTACGGACTCCTCTGGCAGTATTGCAGAGCCGCTTAGAGACGCTCTTTCGTAAGCCTGAAGCTAC
AATTATGCAGAGCAGTGAAAATATTGCTTCTAGCTTGGATGAAGTACGGAATATGCGCTTGCTGACGACCAATCTGCTCA
ATCTGGCCCGTCGCGATGATGGCATCAAGCCTCAATATGGTGAAGTTGAACCAGAATTTTTTGATACGACCTTTGCTAAT
TACTGCATTATCGCAAGGGAGAATAAAAAAGCCTTTCATTCAGAAAATATGATCAAGCACCCTATTGTGACCGATCAAAT
TTTTCTCAAACAGCTGATGACCATTCTATTTGACAACGCTATAAAGTATACAGATGATGATGGCGTAATCAGTGTCATGG
CTACTTCGACAGATCGCTACCTTATTTTCCGAGTGGCGGACAATGGTCCTGGTATCAGCGATGAAGATAAGAAGAAGATT
TTTGATCGCTTTTATCGGGTGGATAAGGCTCGGACCCGTCAGAAAGGTGGCTTTGGTCTGGGACTTTCTCTAGCCAAGCA
GATTGTCGATGCTTTCAAGGGCTCTATTTATGTCAAGGACAACAAACCAAAAGGTACGGTCTTTGAAGTTAAACTGCTAC
TGAAAGAAACGAAAAAGCGTTCTGTAAAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(236-301)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(344-454)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.738

99.568

0.605
  ciaH Streptococcus pneumoniae D39

60.738

99.568

0.605
  ciaH Streptococcus pneumoniae R6

60.738

99.568

0.605
  ciaH Streptococcus pneumoniae TIGR4

60.738

99.568

0.605
  ciaH Streptococcus mutans UA159

52.632

98.488

0.518