Detailed information NTG0886538

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: RRU92_RS04625
• Genome accession: NZ_CP135436
• Coordinates: 939857..942010 (-)
• Length: 717 a.a.
• NCBI ID: WP_315640800.1
• Uniprot ID: -
• Organism: Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 934857..947010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RRU92_RS04595 (RRU92_04595)	-	934950..935279 (-)	330	WP_315640793.1	helicase BlpT	-
RRU92_RS04600 (RRU92_04600)	-	935556..935894 (+)	339	WP_248034717.1	LytTR family DNA-binding domain-containing protein	-
RRU92_RS04605 (RRU92_04605)	comE/blpR	935899..936636 (+)	738	WP_315640794.1	LytTR family DNA-binding domain-containing protein	Regulator
RRU92_RS04610 (RRU92_04610)	-	936650..937990 (+)	1341	WP_315640795.1	sensor histidine kinase	-
RRU92_RS04615 (RRU92_04615)	blpC	938270..938428 (-)	159	WP_248034714.1	quorum-sensing system pheromone BlpC	-
RRU92_RS04620 (RRU92_04620)	-	938485..939846 (-)	1362	WP_315640798.1	bacteriocin secretion accessory protein	-
RRU92_RS04625 (RRU92_04625)	comA/nlmT	939857..942010 (-)	2154	WP_315640800.1	peptide cleavage/export ABC transporter BlpA	Regulator
RRU92_RS04630 (RRU92_04630)	-	942533..942745 (+)	213	WP_315640802.1	hypothetical protein	-
RRU92_RS04635 (RRU92_04635)	-	942756..942950 (+)	195	WP_061862669.1	hypothetical protein	-
RRU92_RS04640 (RRU92_04640)	-	943193..944449 (-)	1257	WP_315640803.1	ISL3 family transposase	-
RRU92_RS04645 (RRU92_04645)	tnpA	944679..945148 (+)	470	Protein_862	IS200/IS605 family transposase	-
RRU92_RS04650 (RRU92_04650)	-	945476..945697 (+)	222	WP_248034707.1	leucocin A/sakacin P family class II bacteriocin	-
RRU92_RS04655 (RRU92_04655)	-	945697..945993 (+)	297	WP_248034706.1	bacteriocin immunity protein	-
RRU92_RS04660 (RRU92_04660)	-	946679..946918 (+)	240	WP_315640804.1	ComC/BlpC family peptide pheromone/bacteriocin	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80754.79 Da
• Isoelectric Point: 7.6796

>NTDB_id=886538 RRU92_RS04625 WP_315640800.1 939857..942010(-) (comA/nlmT) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPSLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=886538 RRU92_RS04625 WP_315640800.1 939857..942010(-) (comA/nlmT) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGAACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACCAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAGCAAAAATCTCTCATTGCTTACATCGTTCTCTCAAGCTTATTGGTCACGATTATCAATATCGGTGGTTCTTA
TTATCTTCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TAACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAAAGATTAAGTATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGGGAAATCATTTC
ACGGTTCACAGATGCCAACTCTATCATAGATGCCTTGGCTTCTACCATTCTCTCTCTTTTTCTTGATGTTTCCATTCTGA
TTCTTGTAGGGGGCGTCTTACTTGCACAAAACCCTAGTCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTTGAAAAAATGAACCACGATGTCATGCAAAGTAATTCTATGGTTAGTTCTGCCAT
CATCGAAGATATTAACGGGATTGAAACCATCAAGTCACTCACAAGTGAAGAAAATCGCTACCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAGTCCTTTAAACTCAGCAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGCTTGAACGAGGTCTATTTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCTAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGTGGTAATCATATGATTAG
CCAAGAAGATATTCTAAAAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.748	99.721	0.715
comA	Streptococcus mitis NCTC 12261	66.339	99.442	0.66
comA	Streptococcus gordonii str. Challis substr. CH1	65.32	100	0.654
comA	Streptococcus pneumoniae Rx1	65.778	99.442	0.654
comA	Streptococcus pneumoniae D39	65.778	99.442	0.654
comA	Streptococcus pneumoniae R6	65.778	99.442	0.654
comA	Streptococcus mitis SK321	65.778	99.442	0.654
comA	Streptococcus pneumoniae TIGR4	65.498	99.442	0.651