Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   RRU92_RS04605 Genome accession   NZ_CP135436
Coordinates   935899..936636 (+) Length   245 a.a.
NCBI ID   WP_315640794.1    Uniprot ID   A0AA96MS33
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 930899..941636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS04570 (RRU92_04570) - 931351..932004 (-) 654 WP_315640785.1 hypothetical protein -
  RRU92_RS04575 (RRU92_04575) - 932090..932377 (-) 288 WP_315640786.1 hypothetical protein -
  RRU92_RS04580 (RRU92_04580) - 932387..932797 (-) 411 WP_315640788.1 HIT family protein -
  RRU92_RS04585 (RRU92_04585) pptA 932865..933596 (+) 732 WP_315640790.1 ABC transporter ATP-binding protein Regulator
  RRU92_RS04590 (RRU92_04590) pptB 933593..934642 (+) 1050 WP_315640792.1 ABC transporter permease Regulator
  RRU92_RS04595 (RRU92_04595) - 934950..935279 (-) 330 WP_315640793.1 helicase BlpT -
  RRU92_RS04600 (RRU92_04600) - 935556..935894 (+) 339 WP_248034717.1 LytTR family DNA-binding domain-containing protein -
  RRU92_RS04605 (RRU92_04605) comE/blpR 935899..936636 (+) 738 WP_315640794.1 LytTR family DNA-binding domain-containing protein Regulator
  RRU92_RS04610 (RRU92_04610) - 936650..937990 (+) 1341 WP_315640795.1 sensor histidine kinase -
  RRU92_RS04615 (RRU92_04615) blpC 938270..938428 (-) 159 WP_248034714.1 quorum-sensing system pheromone BlpC -
  RRU92_RS04620 (RRU92_04620) - 938485..939846 (-) 1362 WP_315640798.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28795.08 Da        Isoelectric Point: 6.7559

>NTDB_id=886537 RRU92_RS04605 WP_315640794.1 935899..936636(+) (comE/blpR) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MRIFVLEDDFSQQARIEKTIEKLLKKQSIIPSSFEVFGKTDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLADDCFYFKSKFAQFQYPFKEVYY
LETSPRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPTNVVRLDKKEKLLFFPNGGSCLIARYKVREVSEV
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=886537 RRU92_RS04605 WP_315640794.1 935899..936636(+) (comE/blpR) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGAGAATTTTTGTTTTAGAAGATGATTTTTCCCAACAAGCCAGAATTGAAAAGACGATTGAAAAACTTTTGAAAAAACA
GAGTATCATTCCCAGTTCTTTTGAAGTTTTCGGGAAAACAGACCAACTGCTGGCAGAGGTGCATGAGAAGGGTGCGCATC
AGCTTTTCTTTTTGGACATTGAGATTCGAAACGAAGAGATGAAGGGGCTAGAAGTGGCTAGAAAGATTCGAGATCGAGAT
CCTTATGCCCTAATCGTCTTTGTGACGACTCACTCAGAGTTTATGCCCCTGTCTTTTCGCTACCAAGTTTCAGCTTTGGA
CTACATTGATAAGGCCTTGTCGGCAGAGGAGTTTGAATCTCGCATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGACGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACATCCCCAAGACCCCATCGTGTTATCCTCTATACCAAGACAGACAGGTTGGAATTTACGGCGAGTTTAGAGGA
GGTTCTCAAGCAGGAGCCACGTCTCTTGCAGTGCCATCGCTCCTTCCTCATCAATCCAACCAATGTAGTTCGTTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGCTGTCTGATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGTT
ATCAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.086

99.184

0.527
  comE/comE1 Streptococcus equinus JB1

42.616

96.735

0.412
  comE/comE2 Streptococcus equinus JB1

38.843

98.776

0.384