Detailed information
Bioinformatically predicted
Overview
| Name | comYD | Type | Machinery gene |
| Locus tag | QN325_RS00945 | Genome accession | NZ_CP135101 |
| Coordinates | 171705..172118 (-) | Length | 137 a.a. |
| NCBI ID | WP_000244261.1 | Uniprot ID | - |
| Organism | Streptococcus agalactiae strain HU13/21 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 126732..170844 | 171705..172118 | flank | 861 |
Gene organization within MGE regions
Location: 126732..172118
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QN325_RS00680 (QN325_00680) | - | 126853..127143 (-) | 291 | WP_000158581.1 | DUF5962 family protein | - |
| QN325_RS00685 (QN325_00685) | - | 127154..128008 (-) | 855 | WP_018368155.1 | phage replisome organizer N-terminal domain-containing protein | - |
| QN325_RS00690 (QN325_00690) | - | 128020..128304 (-) | 285 | WP_001287945.1 | hypothetical protein | - |
| QN325_RS00695 (QN325_00695) | - | 128451..128969 (+) | 519 | WP_000181342.1 | helix-turn-helix domain-containing protein | - |
| QN325_RS00700 (QN325_00700) | - | 129024..130178 (+) | 1155 | WP_410530729.1 | tyrosine-type recombinase/integrase | - |
| QN325_RS00705 (QN325_00705) | rpsI | 130322..130714 (-) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| QN325_RS00710 (QN325_00710) | rplM | 130735..131181 (-) | 447 | WP_001865567.1 | 50S ribosomal protein L13 | - |
| QN325_RS00715 (QN325_00715) | - | 131406..131525 (-) | 120 | Protein_121 | transcriptional regulator | - |
| QN325_RS00720 (QN325_00720) | - | 132062..132922 (-) | 861 | WP_000143135.1 | DegV family protein | - |
| QN325_RS00725 (QN325_00725) | - | 133015..133533 (-) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| QN325_RS00730 (QN325_00730) | rlmB | 133530..134285 (-) | 756 | WP_000178026.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| QN325_RS00735 (QN325_00735) | - | 134388..134774 (-) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| QN325_RS00740 (QN325_00740) | cysS | 134767..136110 (-) | 1344 | WP_000591131.1 | cysteine--tRNA ligase | - |
| QN325_RS00745 (QN325_00745) | - | 136107..136289 (-) | 183 | WP_000656476.1 | lipoprotein | - |
| QN325_RS00750 (QN325_00750) | cysE | 136299..136883 (-) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| QN325_RS00755 (QN325_00755) | - | 136892..137644 (-) | 753 | WP_000204782.1 | SseB family protein | - |
| QN325_RS00760 (QN325_00760) | pnp | 137646..139775 (-) | 2130 | WP_000043850.1 | polyribonucleotide nucleotidyltransferase | - |
| QN325_RS00765 (QN325_00765) | rpsO | 140156..140425 (-) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| QN325_RS00770 (QN325_00770) | - | 140513..141772 (-) | 1260 | WP_001203071.1 | ferric reductase-like transmembrane domain-containing protein | - |
| QN325_RS00775 (QN325_00775) | - | 141881..142810 (-) | 930 | WP_001203821.1 | transketolase family protein | - |
| QN325_RS00780 (QN325_00780) | - | 142807..143664 (-) | 858 | WP_000203489.1 | transketolase | - |
| QN325_RS00785 (QN325_00785) | - | 143667..145022 (-) | 1356 | WP_000677358.1 | PTS ascorbate transporter subunit IIC | - |
| QN325_RS00790 (QN325_00790) | - | 145035..145319 (-) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| QN325_RS00795 (QN325_00795) | - | 145322..147355 (-) | 2034 | WP_000228184.1 | BglG family transcription antiterminator | - |
| QN325_RS00800 (QN325_00800) | treC | 147571..149196 (-) | 1626 | WP_000151017.1 | alpha,alpha-phosphotrehalase | - |
| QN325_RS00805 (QN325_00805) | treP | 149418..151448 (-) | 2031 | WP_000434616.1 | PTS system trehalose-specific EIIBC component | - |
| QN325_RS00810 (QN325_00810) | - | 151731..152357 (-) | 627 | WP_000171311.1 | ABC transporter ATP-binding protein | - |
| QN325_RS00815 (QN325_00815) | - | 152341..153144 (-) | 804 | WP_000140984.1 | ABC transporter ATP-binding protein | - |
| QN325_RS00820 (QN325_00820) | - | 153156..153977 (-) | 822 | WP_000603397.1 | ABC transporter permease | - |
| QN325_RS00825 (QN325_00825) | - | 153974..154951 (-) | 978 | WP_000680645.1 | ABC transporter permease | - |
| QN325_RS00830 (QN325_00830) | - | 155064..156692 (-) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| QN325_RS00835 (QN325_00835) | lrgB | 156935..157663 (-) | 729 | WP_000421726.1 | antiholin-like protein LrgB | - |
| QN325_RS00840 (QN325_00840) | - | 157665..158120 (-) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| QN325_RS00845 (QN325_00845) | - | 158290..159030 (-) | 741 | WP_000697630.1 | LytR/AlgR family response regulator transcription factor | - |
| QN325_RS00850 (QN325_00850) | - | 159011..160756 (-) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| QN325_RS00855 (QN325_00855) | - | 160783..161427 (-) | 645 | WP_000416611.1 | HAD family hydrolase | - |
| QN325_RS00860 (QN325_00860) | ssbA | 161551..161946 (-) | 396 | WP_000282447.1 | single-stranded DNA-binding protein | Machinery gene |
| QN325_RS00865 (QN325_00865) | - | 162027..162743 (+) | 717 | WP_000186185.1 | class I SAM-dependent methyltransferase | - |
| QN325_RS00870 (QN325_00870) | ytpR | 162797..163423 (-) | 627 | WP_000578328.1 | YtpR family tRNA-binding protein | - |
| QN325_RS00875 (QN325_00875) | - | 163456..163779 (-) | 324 | WP_000602781.1 | thioredoxin family protein | - |
| QN325_RS00880 (QN325_00880) | - | 163776..164060 (-) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| QN325_RS00885 (QN325_00885) | - | 164220..164459 (+) | 240 | WP_000660180.1 | hypothetical protein | - |
| QN325_RS00890 (QN325_00890) | pepA | 164644..165711 (+) | 1068 | WP_001281323.1 | glutamyl aminopeptidase | - |
| QN325_RS00895 (QN325_00895) | proC | 165781..166551 (+) | 771 | WP_001865901.1 | pyrroline-5-carboxylate reductase | - |
| QN325_RS00900 (QN325_00900) | - | 166572..167237 (-) | 666 | WP_000008113.1 | CPBP family intramembrane glutamic endopeptidase | - |
| QN325_RS00905 (QN325_00905) | - | 167306..167761 (-) | 456 | WP_000905673.1 | hypothetical protein | - |
| QN325_RS00910 (QN325_00910) | - | 167802..167939 (-) | 138 | WP_001865900.1 | hypothetical protein | - |
| QN325_RS00915 (QN325_00915) | - | 167998..168204 (-) | 207 | WP_000798241.1 | helix-turn-helix transcriptional regulator | - |
| QN325_RS00920 (QN325_00920) | - | 168356..169549 (-) | 1194 | WP_000047534.1 | acetate kinase | - |
| QN325_RS00925 (QN325_00925) | comYH | 169581..170555 (-) | 975 | WP_001008574.1 | class I SAM-dependent methyltransferase | Machinery gene |
| QN325_RS00930 (QN325_00930) | comGG | 170670..171041 (-) | 372 | WP_000601104.1 | competence type IV pilus minor pilin ComGG | - |
| QN325_RS00935 (QN325_00935) | comGF | 171019..171480 (-) | 462 | WP_001878820.1 | competence type IV pilus minor pilin ComGF | - |
| QN325_RS00940 (QN325_00940) | comGE | 171434..171733 (-) | 300 | WP_000234804.1 | competence type IV pilus minor pilin ComGE | - |
| QN325_RS00945 (QN325_00945) | comYD | 171705..172118 (-) | 414 | WP_000244261.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
Sequence
Protein
Download Length: 137 a.a. Molecular weight: 15968.43 Da Isoelectric Point: 9.9787
>NTDB_id=885252 QN325_RS00945 WP_000244261.1 171705..172118(-) (comYD) [Streptococcus agalactiae strain HU13/21]
MVLRKFQVKAFTVLESLIVLSVVAFMTLVFSTSFNNIFRQVEETIFFISFEHLYRDTQKLSAFGQKKQTLTISHNYLENT
YERLYLPKTVKVVKSDTLAFDTNGGNSSLAKIQFECYRKTVTYQLYIGSGNYRKKEN
MVLRKFQVKAFTVLESLIVLSVVAFMTLVFSTSFNNIFRQVEETIFFISFEHLYRDTQKLSAFGQKKQTLTISHNYLENT
YERLYLPKTVKVVKSDTLAFDTNGGNSSLAKIQFECYRKTVTYQLYIGSGNYRKKEN
Nucleotide
Download Length: 414 bp
>NTDB_id=885252 QN325_RS00945 WP_000244261.1 171705..172118(-) (comYD) [Streptococcus agalactiae strain HU13/21]
ATGGTTCTCAGAAAATTTCAAGTTAAAGCATTTACTGTTTTGGAGAGCCTTATTGTATTATCAGTAGTGGCATTTATGAC
GTTAGTATTTTCAACATCATTTAATAATATTTTTAGGCAGGTTGAAGAAACAATTTTCTTCATATCCTTTGAACATCTTT
ATAGAGATACTCAGAAATTGAGTGCATTTGGTCAGAAGAAACAAACCCTTACAATCTCTCATAATTATCTCGAAAATACT
TATGAGAGACTTTATTTACCTAAAACTGTAAAAGTAGTCAAAAGTGATACACTTGCATTTGACACTAATGGAGGGAATTC
AAGCTTGGCAAAAATTCAATTTGAATGTTATAGAAAAACTGTCACGTATCAATTATATATAGGAAGTGGTAATTATCGTA
AGAAAGAAAATTAG
ATGGTTCTCAGAAAATTTCAAGTTAAAGCATTTACTGTTTTGGAGAGCCTTATTGTATTATCAGTAGTGGCATTTATGAC
GTTAGTATTTTCAACATCATTTAATAATATTTTTAGGCAGGTTGAAGAAACAATTTTCTTCATATCCTTTGAACATCTTT
ATAGAGATACTCAGAAATTGAGTGCATTTGGTCAGAAGAAACAAACCCTTACAATCTCTCATAATTATCTCGAAAATACT
TATGAGAGACTTTATTTACCTAAAACTGTAAAAGTAGTCAAAAGTGATACACTTGCATTTGACACTAATGGAGGGAATTC
AAGCTTGGCAAAAATTCAATTTGAATGTTATAGAAAAACTGTCACGTATCAATTATATATAGGAAGTGGTAATTATCGTA
AGAAAGAAAATTAG
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYD | Streptococcus mutans UA140 |
51.515 |
96.35 |
0.496 |
| comYD | Streptococcus mutans UA159 |
51.515 |
96.35 |
0.496 |
| comYD | Streptococcus gordonii str. Challis substr. CH1 |
47.407 |
98.54 |
0.467 |
| comGD/cglD | Streptococcus mitis NCTC 12261 |
41.045 |
97.81 |
0.401 |
| comGD/cglD | Streptococcus pneumoniae TIGR4 |
43.307 |
92.701 |
0.401 |
| comGD/cglD | Streptococcus mitis SK321 |
43.307 |
92.701 |
0.401 |
| comGD/cglD | Streptococcus pneumoniae Rx1 |
42.52 |
92.701 |
0.394 |
| comGD/cglD | Streptococcus pneumoniae D39 |
42.52 |
92.701 |
0.394 |
| comGD/cglD | Streptococcus pneumoniae R6 |
42.52 |
92.701 |
0.394 |