Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   RMP64_RS04975 Genome accession   NZ_CP135093
Coordinates   992082..992924 (-) Length   280 a.a.
NCBI ID   WP_002936492.1    Uniprot ID   -
Organism   Streptococcus suis strain 1652329     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 992764..1021311 992082..992924 flank -160


Gene organization within MGE regions


Location: 992082..1021311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP64_RS04975 (RMP64_04975) dprA 992082..992924 (-) 843 WP_002936492.1 DNA-processing protein DprA Machinery gene
  RMP64_RS04980 (RMP64_04980) - 992983..993444 (-) 462 Protein_952 sugar O-acetyltransferase -
  RMP64_RS04985 (RMP64_04985) - 993586..993897 (+) 312 WP_014637902.1 rhodanese-like domain-containing protein -
  RMP64_RS04990 (RMP64_04990) - 993994..994545 (+) 552 WP_024394485.1 DUF1836 domain-containing protein -
  RMP64_RS04995 (RMP64_04995) - 994535..995185 (+) 651 WP_002936498.1 hemolysin III family protein -
  RMP64_RS05000 (RMP64_05000) - 995218..996228 (-) 1011 WP_029174502.1 YdcF family protein -
  RMP64_RS05005 (RMP64_05005) - 996231..997004 (-) 774 WP_024387771.1 ribonuclease HII -
  RMP64_RS05010 (RMP64_05010) ylqF 996991..997842 (-) 852 WP_024394486.1 ribosome biogenesis GTPase YlqF -
  RMP64_RS05015 (RMP64_05015) - 997934..999454 (-) 1521 WP_024394487.1 tyrosine-type recombinase/integrase -
  RMP64_RS05020 (RMP64_05020) - 999544..999783 (-) 240 WP_004195677.1 hypothetical protein -
  RMP64_RS05025 (RMP64_05025) - 1000069..1000296 (-) 228 WP_023370317.1 helix-turn-helix domain-containing protein -
  RMP64_RS05030 (RMP64_05030) - 1000559..1003486 (-) 2928 WP_024394488.1 glycoside hydrolase family 98 domain-containing protein -
  RMP64_RS05035 (RMP64_05035) - 1003609..1004502 (-) 894 WP_024394489.1 ROK family protein -
  RMP64_RS05040 (RMP64_05040) - 1004512..1006374 (-) 1863 WP_024394490.1 alpha-N-acetylgalactosaminidase -
  RMP64_RS05045 (RMP64_05045) - 1006377..1007699 (-) 1323 WP_029174503.1 alpha-L-fucosidase -
  RMP64_RS05050 (RMP64_05050) - 1007696..1008535 (-) 840 WP_024394492.1 carbohydrate ABC transporter permease -
  RMP64_RS05055 (RMP64_05055) - 1008545..1009465 (-) 921 WP_024394493.1 carbohydrate ABC transporter permease -
  RMP64_RS05060 (RMP64_05060) - 1009524..1010831 (-) 1308 WP_024394494.1 ABC transporter substrate-binding protein -
  RMP64_RS05065 (RMP64_05065) - 1010851..1011504 (-) 654 WP_043032844.1 L-fuculose-phosphate aldolase -
  RMP64_RS05070 (RMP64_05070) - 1011518..1013305 (-) 1788 WP_087013869.1 L-fucose isomerase -
  RMP64_RS05075 (RMP64_05075) - 1013307..1014704 (-) 1398 WP_029750033.1 rhamnulokinase family protein -
  RMP64_RS10860 - 1014867..1015199 (+) 333 WP_024394497.1 DeoR family transcriptional regulator -
  RMP64_RS10865 mobC 1015145..1015630 (+) 486 WP_172005789.1 plasmid mobilization relaxosome protein MobC -
  RMP64_RS05090 (RMP64_05090) - 1015632..1016927 (+) 1296 WP_024394500.1 relaxase/mobilization nuclease domain-containing protein -
  RMP64_RS05095 (RMP64_05095) - 1016930..1017427 (-) 498 WP_024394501.1 hypothetical protein -
  RMP64_RS05100 (RMP64_05100) - 1017591..1018283 (+) 693 WP_024394502.1 XRE family transcriptional regulator -
  RMP64_RS05105 (RMP64_05105) - 1018286..1018420 (+) 135 WP_087013866.1 hypothetical protein -
  RMP64_RS05110 (RMP64_05110) - 1018426..1019840 (+) 1415 Protein_978 Y-family DNA polymerase -
  RMP64_RS05115 (RMP64_05115) - 1019837..1020205 (+) 369 WP_024394503.1 hypothetical protein -
  RMP64_RS05120 (RMP64_05120) - 1020192..1020506 (+) 315 WP_024394504.1 DUF5960 family protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31261.11 Da        Isoelectric Point: 8.4451

>NTDB_id=885034 RMP64_RS04975 WP_002936492.1 992082..992924(-) (dprA) [Streptococcus suis strain 1652329]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAIVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=885034 RMP64_RS04975 WP_002936492.1 992082..992924(-) (dprA) [Streptococcus suis strain 1652329]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGAAAAAAATTGACCTTGCGAAATGTCGCTATAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCGCCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
TGCAGTCGTTGGTACACGAAATGCCAGCAAAAATGGTATTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCTCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCTGTAATTGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAAGATTTGCAGACCTATATCGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGAAATCGCATCATTGCTGGGTTGG
TAGAAGGATTGGTAGTCTGTGAGGCTAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

69.286

100

0.693
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis SK321

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.571

100

0.636
  dprA Lactococcus lactis subsp. cremoris KW2

60.357

100

0.604
  dprA Legionella pneumophila strain ERS1305867

41.7

88.214

0.368
  dprA Bacillus subtilis subsp. subtilis str. 168

50.746

71.786

0.364