Detailed information NTG0884992

Bioinformatically predicted

Overview

• Name: micA
• Type: Regulator
• Locus tag: RMQ61_RS08075
• Genome accession: NZ_CP135090
• Coordinates: 1651125..1651829 (-)
• Length: 234 a.a.
• NCBI ID: WP_004298854.1
• Uniprot ID: A0A0K2E6P6
• Organism: Streptococcus suis strain ID48908
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1646125..1656829

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMQ61_RS08045 (RMQ61_08050)	-	1646240..1646416 (-)	177	WP_398584291.1	hypothetical protein	-
RMQ61_RS08050 (RMQ61_08055)	-	1646650..1647291 (-)	642	WP_029749608.1	hypothetical protein	-
RMQ61_RS08055 (RMQ61_08060)	-	1647368..1647667 (-)	300	WP_313919733.1	hypothetical protein	-
RMQ61_RS08060 (RMQ61_08065)	-	1647973..1648614 (-)	642	WP_313919736.1	ATP-binding cassette domain-containing protein	-
RMQ61_RS08065 (RMQ61_08070)	vicX	1648973..1649776 (-)	804	WP_002935843.1	MBL fold metallo-hydrolase	Regulator
RMQ61_RS08070 (RMQ61_08075)	micB	1649783..1651132 (-)	1350	WP_044761697.1	cell wall metabolism sensor histidine kinase VicK	Regulator
RMQ61_RS08075 (RMQ61_08080)	micA	1651125..1651829 (-)	705	WP_004298854.1	response regulator YycF	Regulator
RMQ61_RS08080 (RMQ61_08085)	-	1652023..1652784 (+)	762	WP_313919738.1	amino acid ABC transporter ATP-binding protein	-
RMQ61_RS08085 (RMQ61_08090)	-	1652795..1653634 (+)	840	WP_313919740.1	transporter substrate-binding domain-containing protein	-
RMQ61_RS08090 (RMQ61_08095)	-	1653649..1654347 (+)	699	WP_313919742.1	amino acid ABC transporter permease	-
RMQ61_RS08095 (RMQ61_08100)	-	1654362..1655021 (+)	660	WP_313919744.1	amino acid ABC transporter permease	-
RMQ61_RS11780	-	1655269..1655568 (+)	300	WP_398584292.1	acyltransferase family protein	-
RMQ61_RS08100 (RMQ61_08105)	-	1655532..1656326 (+)	795	WP_313919749.1	acyltransferase family protein	-

Sequence

Protein

• Length: 234 a.a.
• Molecular weight: 26781.77 Da
• Isoelectric Point: 4.8957

>NTDB_id=884992 RMQ61_RS08075 WP_004298854.1 1651125..1651829(-) (micA) [Streptococcus suis strain ID48908]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide

• Length: 705 bp

>NTDB_id=884992 RMQ61_RS08075 WP_004298854.1 1651125..1651829(-) (micA) [Streptococcus suis strain ID48908]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGTGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTAATTGGCGATTTAGTCATTTTACCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (154-229)

• Response regulator receiver domain (Response_reg) (4-112)

3D structure

• AlphaFold DB: A0A0K2E6P6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micA	Streptococcus pneumoniae Cp1015	81.974	99.573	0.816
vicR	Streptococcus mutans UA159	80.426	100	0.808
covR	Lactococcus lactis subsp. lactis strain DGCC12653	44.783	98.291	0.44
covR	Streptococcus salivarius strain HSISS4	43.723	98.718	0.432
scnR	Streptococcus mutans UA159	38.095	98.718	0.376