Detailed information NTG0884702

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: RMQ63_RS09760
• Genome accession: NZ_CP135063
• Coordinates: 2021490..2022161 (+)
• Length: 223 a.a.
• NCBI ID: WP_029186691.1
• Uniprot ID: A0AB33UFN5
• Organism: Streptococcus suis strain ID32563
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2016490..2027161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMQ63_RS09730 (RMQ63_09730)	pstC	2016594..2017511 (+)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-
RMQ63_RS09735 (RMQ63_09735)	pstA	2017501..2018388 (+)	888	WP_014635996.1	phosphate ABC transporter permease PstA	-
RMQ63_RS09740 (RMQ63_09740)	pstB	2018413..2019216 (+)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
RMQ63_RS09745 (RMQ63_09745)	pstB	2019228..2019986 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
RMQ63_RS09750 (RMQ63_09750)	phoU	2020015..2020671 (+)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
RMQ63_RS09755 (RMQ63_09755)	-	2020837..2021298 (+)	462	WP_105242436.1	hypothetical protein	-
RMQ63_RS09760 (RMQ63_09760)	ciaR	2021490..2022161 (+)	672	WP_029186691.1	response regulator transcription factor	Regulator
RMQ63_RS09765 (RMQ63_09765)	ciaH	2022154..2023533 (+)	1380	WP_105135003.1	cell wall metabolism sensor histidine kinase WalK	Regulator
RMQ63_RS09770 (RMQ63_09770)	-	2023634..2024863 (+)	1230	WP_105136222.1	transglutaminase domain-containing protein	-
RMQ63_RS09775 (RMQ63_09775)	rpsT	2025127..2025375 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
RMQ63_RS09780 (RMQ63_09780)	coaA	2025434..2026354 (-)	921	WP_313680854.1	type I pantothenate kinase	-
RMQ63_RS09785 (RMQ63_09785)	-	2026463..2027053 (+)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25227.85 Da
• Isoelectric Point: 4.2183

>NTDB_id=884702 RMQ63_RS09760 WP_029186691.1 2021490..2022161(+) (ciaR) [Streptococcus suis strain ID32563]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLIFGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=884702 RMQ63_RS09760 WP_029186691.1 2021490..2022161(+) (ciaR) [Streptococcus suis strain ID32563]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGCCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTACGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACACCTGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGCAAGTTTAATGAAAACACACTAATTTTTGGAGACGTGACTG
TTGACTTATCGACAAACTCCACAACTGTAAATGGCGAAGAAGTCGAATTGCTAGGAAAAGAATTCGATCTACTAGTCTAC
TTCTTGCAAAATCAAAATGTTATCTTACCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	89.238	100	0.892
ciaR	Streptococcus pneumoniae Rx1	87.892	100	0.879
ciaR	Streptococcus pneumoniae D39	87.892	100	0.879
ciaR	Streptococcus pneumoniae R6	87.892	100	0.879
ciaR	Streptococcus pneumoniae TIGR4	87.892	100	0.879
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.897	100	0.377