Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   RMQ63_RS09765 Genome accession   NZ_CP135063
Coordinates   2022154..2023533 (+) Length   459 a.a.
NCBI ID   WP_105135003.1    Uniprot ID   -
Organism   Streptococcus suis strain ID32563     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2017154..2028533
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ63_RS09735 (RMQ63_09735) pstA 2017501..2018388 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  RMQ63_RS09740 (RMQ63_09740) pstB 2018413..2019216 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  RMQ63_RS09745 (RMQ63_09745) pstB 2019228..2019986 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  RMQ63_RS09750 (RMQ63_09750) phoU 2020015..2020671 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  RMQ63_RS09755 (RMQ63_09755) - 2020837..2021298 (+) 462 WP_105242436.1 hypothetical protein -
  RMQ63_RS09760 (RMQ63_09760) ciaR 2021490..2022161 (+) 672 WP_029186691.1 response regulator transcription factor Regulator
  RMQ63_RS09765 (RMQ63_09765) ciaH 2022154..2023533 (+) 1380 WP_105135003.1 cell wall metabolism sensor histidine kinase WalK Regulator
  RMQ63_RS09770 (RMQ63_09770) - 2023634..2024863 (+) 1230 WP_105136222.1 transglutaminase domain-containing protein -
  RMQ63_RS09775 (RMQ63_09775) rpsT 2025127..2025375 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  RMQ63_RS09780 (RMQ63_09780) coaA 2025434..2026354 (-) 921 WP_313680854.1 type I pantothenate kinase -
  RMQ63_RS09785 (RMQ63_09785) - 2026463..2027053 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  RMQ63_RS09790 (RMQ63_09790) - 2027050..2028327 (+) 1278 WP_029188320.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51959.63 Da        Isoelectric Point: 6.1945

>NTDB_id=884703 RMQ63_RS09765 WP_105135003.1 2022154..2023533(+) (ciaH) [Streptococcus suis strain ID32563]
MPKRIRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLLLDKEKLGEIKEATVESSFGM
SEDYRYVTIELAIDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=884703 RMQ63_RS09765 WP_105135003.1 2022154..2023533(+) (ciaH) [Streptococcus suis strain ID32563]
ATGCCTAAGCGAATCAGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATTATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCCGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACTGTTAGATAAGGAAAAATTGGGTGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTATAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAGATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTTATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGCTATCAAAAACAA
AAGGACTTTGTCGAAAATGCTAGTCATGAGTTGCGTACGCCGCTGGCTGTTCTCCAAAATCGTTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACTTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCGAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTCACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACACGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGTTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGACTACCTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.676

100

0.501
  ciaH Streptococcus pneumoniae D39

49.676

100

0.501
  ciaH Streptococcus pneumoniae R6

49.676

100

0.501
  ciaH Streptococcus pneumoniae TIGR4

49.676

100

0.501
  ciaH Streptococcus mutans UA159

49.89

99.129

0.495